Dioxaphosphorinane-Constrained Nucleic Acid Dinucleotides as Tools for Structural Tuning of Nucleic Acids
Figure 1
Examples of DNA secondary structures and associated backbone-torsion angles γ/β/α/ε/ζ of representative dinucleotide units. The following 6-fold staggered pattern of the torsional angles is used: cis = ° (c), gauche(+) = ° (g+), anticlinal(+) = ° (a+), trans = ° (), anticlinal(−) = ° (a−), and gauche(−) = ° (g−). The notation g−/a− is used to designate a torsion angle on the border of gauche(−) and anticlinal(−). PDB ID: Hairpin, 1ii1; duplex, 436d; Bulge, 1jrv; 4-Way junction, 1zez, and G-quad, 1kf1.
