Inhibition of HIV Replication by Cyclic and Hairpin PNAs Targeting the HIV-1 TAR RNA Loop

Figure 1

Sequence and secondary structure of (a) HIV-1 mini-TAR RNA, (b) R06₂₄ and R06₁₈ aptamers reported in this study. Bold bases indicate complementarity between aptamer and TAR loops. The crucial G and A residues flanking the R06 aptamers loop are in italics.

(a)

(b)