Journal of Nucleic Acids / 2012 / Article / Fig 4

Research Article

Superior Silencing by 2′,4′-BNANC-Based Short Antisense Oligonucleotides Compared to 2′,4′-BNA/LNA-Based Apolipoprotein B Antisense Inhibitors

Figure 4

Relationship between target affinity and antisense potency. IC50 as a function of values of 2′,4′- -based AONs (solid line) and 2′,4′-BNA/LNA-based AONs (dotted line).

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