Alternative Splicing of Fibroblast Growth Factor Receptor IgIII Loops in Cancer

Table 1

Ligand-binding pattern of FGFR IIIb and IIIc isoforms [8].

Receptor	Ligands binding
	IIIb	IIIc
FGFR1	FGF1, FGF2, FGF3, FGF10, FGF22	FGF1, FGF2, FGF4, FGF5, FGF6, FGF8, FGF9, FGF16, FGF17, FGF18, FGF20, FGF21, FGF23
FGFR2	FGF1, FGF3, FGF7, FGF10, FGF22	FGF1, FGF2, FGF4, FGF5, FGF6, FGF8, FGF9, FGF16, FGF17, FGF18, FGF20, FGF21, FGF23
FGFR3	FGF1, FGF9, FGF16	FGF1, FGF2, FGF4, FGF5, FGF6, FGF8, FGF9, FGF16, FGF17, FGF18, FGF20, FGF21