Journal of Nucleic Acids / 2012 / Article / Tab 4

Research Article

Genetic Predisposition for Dermal Problems in Hexavalent Chromium Exposed Population

Table 4

Influence of various covariates and genotypes on dermatological adversities among exposed group compared with asymptomatic control group.

CharactersCategoryExposed SYMPControl ASYMPOR (95% CI)
( 𝑁 = 3 8 ) 𝑛 (%)( 𝑁 = 1 4 8 ) 𝑛 (%)

SexMales20 (52.6)65 (43.9)1
Females18 (47.4)83 (56.1)0.71 (0.345–1.441)

Age (years)≀3520 (52.6)69 (46.6)1
>3518 (47.4)79 (53.4)0.67 (0.408–1.109)

SmokingNever30 (79)135 (91.2)1
Current/past8 (21)13 (8.8)2.77 (1.055–7.272)*

GSTT1Wild27 (71)127 (85.8)1
Null11 (29)21 (14.2)2.46 (1.064–5.705)*
2.53 (0.946–6.77)#

GSTM1Wild24 (63.2)92 (62.2)1
Null14 (36.8)56 (37.8)0.96 (0.458–2.005)

NQO1Wild (C/C)16 (44.4)72 (48.65)1
Mutant (C/T + T/T)20 (55.6)76 (51.35)1.18 (0.569–2.463)

hOGG1Wild (C/C)13 (34.2)54 (36.5)1
Mutant (C/G + G/G)25 (65.8)94 (63.5)0.905 (0.428–1.915)

SYMP: symptomatic, ASYMP: asymptomatic, OR: odds ratio, CI: confidence interval; #odds ratio adjusted for smoking; * 𝑃 < 0 . 0 5 .

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