Journal of Nucleic Acids / 2012 / Article / Tab 5

Research Article

Genetic Predisposition for Dermal Problems in Hexavalent Chromium Exposed Population

Table 5

Influence of various covariates and genotypes on dermatological adversities among symptomatic exposed compared with asymptomatic exposed group.

CharactersCategoryExposed SYMPExposed ASYMPOR (95% CI)
( 𝑁 = 3 8 ) 𝑛 (%)( 𝑁 = 1 0 8 ) 𝑛 (%)

SexMales20 (52.6)59 (54.6)1
Females18 (47.4)49 (45.4)1.08 (0.517–2.273)

Age (years)≀3520 (52.6)61 (56.5)1
>3518 (47.4)47 (43.5)1.17 (0.556–2.453

SmokingNever30 (79)88 (81.5)1
Current/past8 (21)20 (18.5)1.17 (0.468–2.94)

Duration of≀2019 (50)62 (57.4)1
residence (years)>2019 (50)46 (42.6)1.35 (0.642–2.83)

GSTT1Wild27 (71)85 (78.7)1
Null11 (29)23 (21.3)1.51 (0.651–3.484)

GSTM1Wild24 (63.2)87 (80.6)1
Null14 (36.8)21 (19.4)2.42 (1.071–5.451)*

NQO1Wild (C/C)16 (44.4)38 (36.2)1
Mutant (C/T + T/T)20 (55.6)67 (63.8)0.71 (0.329–1.529)

hOGG1Wild (C/C)13 (34.2)56 (51.8)1
Mutant (C/G + G/G)25 (65.8)52 (48.2)2.07 (0.96–4.469)

SYMP: symptomatic, ASYMP: asymptomatic, OR: odds ratio, CI: confidence interval; * 𝑃 < 0 . 0 5 .

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