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Journal of Nucleic Acids
Volume 2012, Article ID 971581, 7 pages
Research Article

Combinatorial Synthesis, Screening, and Binding Studies of Highly Functionalized Polyamino-amido Oligomers for Binding to Folded RNA

Laboratory of Bioorganic Chemistry, NIH, NIDDK, Bethesda, MD 20892, USA

Received 1 June 2012; Revised 28 June 2012; Accepted 29 June 2012

Academic Editor: Eriks Rozners

Copyright © 2012 Jonathan K. Pokorski and Daniel H. Appella. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Detailed protocols and data for the solid phase synthesis of PAA trimers, terbium footprinting assays, and monomer characterization are provided.

  1. Supplementary Materials