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Journal of Nucleic Acids
Volume 2014 (2014), Article ID 178350, 9 pages
http://dx.doi.org/10.1155/2014/178350
Research Article

Effects of Stability of Base Pairs Containing an Oxazolone on DNA Elongation

Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, 1314-1 Shido, Sanuki, Kagawa 769-2193, Japan

Received 17 September 2014; Accepted 14 November 2014; Published 7 December 2014

Academic Editor: Hiroshi Sugiyama

Copyright © 2014 Masayo Suzuki et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. F. Maehira, I. Miyagi, T. Asato et al., “Alterations of protein kinase C, 8-hydroxydeoxyguanosine, and K-ras oncogene in rat lungs exposed to passive smoking,” Clinica Chimica Acta, vol. 289, no. 1-2, pp. 133–144, 1999. View at Publisher · View at Google Scholar · View at Scopus
  2. S. Shibutani, M. Takeshita, and A. P. Grollman, “Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG,” Nature, vol. 349, no. 6308, pp. 431–434, 1991. View at Publisher · View at Google Scholar · View at Scopus
  3. J. Cadet, M. Berger, G. W. Buchko, P. C. Joshi, S. Raoul, and J.-L. Ravanat, “2,2-Diamino-4-[(3,5-di-O-acetyl-2-deoxy-β-D-erythro-pentofuranosyl)amino]-5-(2H)-oxazolone: a novel and predominant radical oxidation product of 3′,5′-Di-O-acetyl-2′-deoxyguanosine,” Journal of the American Chemical Society, vol. 116, no. 16, pp. 7403–7404, 1994. View at Publisher · View at Google Scholar · View at Scopus
  4. W. Luo, J. G. Muller, and C. J. Burrows, “The pH-dependent role of superoxide in riboflavin-catalyzed photooxidation of 8-oxo-7,8-dihydroguanosine,” Organic Letters, vol. 3, no. 18, pp. 2801–2804, 2001. View at Publisher · View at Google Scholar · View at Scopus
  5. K. Kino and H. Sugiyama, “Possible cause of G-CC-G transversion mutation by guanine oxidation product, imidazolone,” Chemistry & Biology, vol. 8, no. 4, pp. 369–378, 2001. View at Publisher · View at Google Scholar · View at Scopus
  6. B. Matter, D. Malejka-Giganti, A. S. Csallany, and N. Tretyakova, “Quantitative analysis of the oxidative DNA lesion, 2,2-diamino-4-(2-deoxy-β-D-erythro-pentofuranosyl) amino]-5(2H)-oxazolone (oxazolone), in vitro and in vivo by isotope dilution-capillary HPLC-ESI-MS/MS,” Nucleic Acids Research, vol. 34, no. 19, pp. 5449–5460, 2006. View at Publisher · View at Google Scholar · View at Scopus
  7. K. Kino, N. Ito, K. Sugasawa, H. Sugiyama, and F. Hanaoka, “Translesion synthesis by human DNA polymerase eta across oxidative products of guanine,” Nucleic Acids Symposium Series, vol. 48, pp. 171–172, 2004. View at Google Scholar
  8. K. Kino, K. Sugasawa, T. Mizuno et al., “Eukaryotic DNA polymerases α, β and ε incorporate guanine opposite 2,2,4-triamino-5(2H)-oxazolone,” ChemBioChem, vol. 10, no. 16, pp. 2613–2616, 2009. View at Publisher · View at Google Scholar · View at Scopus
  9. M. Suzuki, K. Kino, M. Morikawa, T. Kobayashi, R. Komori, and H. Miyazawa, “Calculation of the stabilization energies of oxidatively damaged guanine base pairs with guanine,” Molecules, vol. 17, no. 6, pp. 6705–6715, 2012. View at Publisher · View at Google Scholar · View at Scopus
  10. M. Suzuki, K. Kino, M. Morikawa, T. Kobayashi, and H. Miyazawa, “Calculating distortions of short DNA duplexes with base pairing between an oxidatively damaged guanine and a guanine,” Molecules, vol. 19, no. 8, pp. 11030–11044, 2014. View at Google Scholar
  11. L. Yang, W. A. Beard, S. H. Wilson, B. Roux, S. Broyde, and T. Schlick, “Local deformations revealed by dynamics simulations of DNA polymerase β with DNA mismatches at the primer terminus,” Journal of Molecular Biology, vol. 321, no. 3, pp. 459–478, 2002. View at Publisher · View at Google Scholar · View at Scopus
  12. W. A. Beard, D. D. Shock, and S. H. Wilson, “Influence of DNA structure on DNA polymerase β active site function: extension of mutagenic DNA intermediates,” The Journal of Biological Chemistry, vol. 279, no. 30, pp. 31921–31929, 2004. View at Publisher · View at Google Scholar · View at Scopus
  13. T. Matsuda, K. Bebenek, C. Masutani, I. B. Rogozin, F. Hanaoka, and T. A. Kunkel, “Error rate and specificity of human and murine DNA polymerase η,” Journal of Molecular Biology, vol. 312, no. 2, pp. 335–346, 2001. View at Publisher · View at Google Scholar · View at Scopus
  14. C. Kano, F. Hanaoka, and J.-Y. Wang, “Analysis of mice deficient in both REV1 catalytic activity and POLH reveals an unexpected role for POLH in the generation of C to g and G to C transversions during Ig gene hypermutation,” International Immunology, vol. 24, no. 3, pp. 169–174, 2012. View at Publisher · View at Google Scholar · View at Scopus
  15. C. Masutani, R. Kusumoto, S. Iwai, and F. Hanaoka, “Mechanisms of accurate translesion synthesis by human DNA polymerase η,” EMBO Journal, vol. 19, no. 12, pp. 3100–3109, 2000. View at Publisher · View at Google Scholar · View at Scopus