In What Ways Do Synthetic Nucleotides and Natural Base Lesions Alter the Structural Stability of G-Quadruplex Nucleic Acids?

Figure 11

The mirror image D- and L-2′-deoxynucleosides (1); the D- (2) and L-iso-thymidines (3); the anti north- and the syn south-bicyclo[..0]hexane-dGs (4); and an acyclic thymine analog, the N¹-(3-hydroxy-2-hydroxymethyl-2-methylpropyl)-thymine (5).