Research Article

A Sequence-Dependent DNA Condensation Induced by Prion Protein

Table 1

Stern-Volmer constant sv for the accessibility of YOYO bound to different DNAs in the presence of α-PrP or spermine in Hepes buffer, pH 7.4 containing 100 mM NaCl.

DNA moleculesBase pairsv mol−1 for [PrP]/[DNA-ph]
or [spermine]/[DNA-ph]
00.63

gcDNA8400.11 0.050.99 0.35
mDNA26580.23 0.04
atDNA35230.44 0.090.81 0.27
SpermineWith gcDNA0.11 0.050.64 0.21