Genotoxic Effects of Etoposide, Bleomycin, and Ethyl Methanesulfonate on Cultured CHO Cells: Analysis by GC-MS/MS and Comet Assay

Figure 2

Comet assay—comparison of treatment with (a) etoposide, (b) bleomycin, and (c) EMS. The data are plotted as box and whiskers, which indicates the 25 and 75 percentiles as the size of the data box, the median % DNA as a horizontal line within the boxes, and the outliers by the max and minimum values of the vertical lines. Approximately 100 cells were counted at each treatment level. The data are from one of three replicates.

(a)

(b)

(c)