Journal of Nucleic Acids

G-Quadruplex Nucleic Acids


Publishing date
15 Jul 2010
Status
Published
Submission deadline
15 Jan 2010

Lead Editor

1Laboratoire de Biophysique, INSERM U565, Museum National d'Histoire Naturelle, Paris, France

2Dipartimento di Chimica Organica e Biochimica, Università degli Studi di Napoli “Federico II”, Naples, Italy

3Department of Complex matter, J. Stefan Institute, Ljubljana, Slovenia

4School of Biomedical Sciences, University of Ulster, UK


G-Quadruplex Nucleic Acids

Description

G-quadruplexes are a family of four-stranded structures stabilized by guanine quartets, in which four planar guanines establish a cyclic array of Hydrogen bonds. They are of special interest due to increasing evidence for their formation in vivo and their possible implication in biology, especially at telomeres and as contributors to gene regulation. Moreover, G-quadruplexes are also formed as a result of self-assembling processes of guanosine derivatives yielding several interesting motifs such as G-ribbons and G-wires which have interesting electrical conductivity properties that are being explored as molecular wires.

We invite authors to submit original research articles as well as review articles that will stimulate the development of this fast growing field. We are interested on manuscripts describing new guanosine derivatives and G-rich oligonucleotides with novel properties as well as characterization of self-assembling properties of guanosine derivatives and G-quadruplex topologies. Studies describing the interactions of G-quadruplexes with proteins or drugs and the study of surfaces functionalized with G-quadruplexes are also welcomed. The topics to be covered include, but are not limited to:

  • Self-assembling properties of guanosine derivatives
  • Design and synthesis of novel guanosine-based materials
  • Theoretical modeling of G-quadruplexes
  • Synthesis and properties of G-rich DNA and RNA oligonucleotides
  • Structural properties of G-quadruplexes
  • Biological recognition of G-quadruplexes
  • Biological functions of G-quadruplexes
  • Drugs that bind G-quadruplexes
  • G-quadruplexes in protein-aptamer interactions
  • G-quadruplexes as drugs and diagnostics
  • Potential applications of G-quadruplexes (electronic, optical properties, nanotechnology, sensors, etc.)

We solicit original unpublished research papers only. Papers previously published in conference/workshop proceedings can be considered, but should be substantially extended.

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jna/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2010
  • - Article ID 147650
  • - Editorial

G-Quadruplex Nucleic Acids

Ramon Eritja | Jean-Louis Mergny | ... | Mateus Webba da Silva
  • Special Issue
  • - Volume 2010
  • - Article ID 938536
  • - Research Article

Hierarchical Formation of Fibrillar and Lamellar Self-Assemblies from Guanosine-Based Motifs

Paolo Neviani | Dominique Sarazin | ... | Gian Piero Spada
  • Special Issue
  • - Volume 2010
  • - Article ID 489736
  • - Research Article

A Comparative Study of the Impact of G-Stack Probes on Various Affymetrix GeneChips of Mammalia

Farhat Naureen Memon | Graham J. G. Upton | Andrew P. Harrison
  • Special Issue
  • - Volume 2010
  • - Article ID 472478
  • - Research Article

Guanosine Quadruplexes in Solution: A Small-Angle X-Ray Scattering Analysis of Temperature Effects on Self-Assembling of Deoxyguanosine Monophosphate

P. Mariani | F. Spinozzi | ... | I. Drevensek-Olenik
  • Special Issue
  • - Volume 2010
  • - Article ID 820356
  • - Research Article

Evaluation of Human Telomeric G-Quadruplexes: The Influence of Overhanging Sequences on Quadruplex Stability and Folding

Viktor Viglasky | Lubos Bauer | ... | Peter Javorsky
  • Special Issue
  • - Volume 2010
  • - Article ID 121259
  • - Research Article

Cation Involvement in Telomestatin Binding to G-Quadruplex DNA

Frédéric Rosu | Valérie Gabelica | ... | Edwin De Pauw
  • Special Issue
  • - Volume 2010
  • - Article ID 841932
  • - Research Article

Thrombin-Binding Aptamer Quadruplex Formation: AFM and Voltammetric Characterization

Victor Constantin Diculescu | Ana-Maria Chiorcea-Paquim | ... | Ana Maria Oliveira-Brett
  • Special Issue
  • - Volume 2010
  • - Article ID 489060
  • - Research Article

Synthesis and G-Quadruplex-Binding Properties of Defined Acridine Oligomers

Rubén Ferreira | Anna Aviñó | ... | Ramon Eritja
  • Special Issue
  • - Volume 2010
  • - Article ID 564946
  • - Review Article

A Toolbox for Predicting G-Quadruplex Formation and Stability

Han Min Wong | Oliver Stegle | ... | Julian Leon Huppert
  • Special Issue
  • - Volume 2010
  • - Article ID 431651
  • - Research Article

Effect of Base Sequence on G-Wire Formation in Solution

Lea Spindler | Martin Rigler | ... | Mateus Webba da Silva
Journal of Nucleic Acids
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