Neuroprotection by Exendin-4 Is GLP-1 Receptor Specific but DA D<sub>3</sub> Receptor Dependent, Causing Altered BrdU Incorporation in Subventricular Zone and Substantia Nigra

<table>Quantified histograms of DAB-stained cell counts from 6 sections from each of the brains in the treatment group (<svg height="11.225" id="M32" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 36.237499 11.225" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>) were used for analysis. DAB cell counts along the wall of the SVZ (a) or SN (b) were carried out manually. Results were analyzed using one-way ANOVA (SVZ <svg height="11.375" id="M33" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.474998 11.375" width="58.474998" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>; SN <svg height="11.375" id="M34" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 66.637497 11.375" width="66.637497" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>) and a post hoc Bonferroni test to compare relevant treatment groups. *<svg height="11.375" id="M35" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> indicates significant difference compared to sham and 6-OHDA + EX-4. **<svg height="11.375" id="M36" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> indicates significant difference compared to 6-OHDA and EX-4 treatment. </table>

Journal of Neurodegenerative Diseases

fig6

Figure 6

Figure 6: Neuroprotection by Exendin-4 Is GLP-1 Receptor Specific but DA D<sub>3</sub> Receptor Dependent, Causing Altered BrdU Incorporation in Subventricular Zone and Substantia Nigra 

Figure 6 | Neuroprotection by Exendin-4 Is GLP-1 Receptor Specific but DA D3 Receptor Dependent, Causing Altered BrdU Incorporation in Subventricular Zone and Substantia Nigra 