Glial Cell Line-Derived Neurotrophic Factor Family Members Reduce Microglial Activation via Inhibiting p38MAPKs-Mediated Inflammatory Responses

Figure 1

Microglia express GFR-𝛼1 and the coreceptor RET. Using qualitative PCR, we investigated whether the GFL receptor GFR-𝛼1 and the coreceptor RET are expressed in primary rat microglial cells. Analysis of the PCR products on an ethidium bromide-stained 2% agarose gel demonstrates the expression of both receptors: GFR-𝛼1 (lane 2) and RET (lane 3). GAPDH cDNA served as control (lane 1).