Valproic Acid Neuroprotection in the 6-OHDA Model of Parkinson’s Disease Is Possibly Related to Its Anti-Inflammatory and HDAC Inhibitory Properties

Figure 3

Valproic acid (VA) treatments partly reverse the decrease of dopamine (DA) and DOPAC contents observed in the untreated 6-OHDA group. Values are mean ± SEM from 8–17 animals per group. DA: a. versus left side (L) of the same group, , ; b. versus left side (L) of the same group, , ; c. versus 6-OHDA, right side (R), , . DOPAC: a. versus left side (L) of the same group, , ; b. versus left side (L) of the same group, , ; c. versus left side (L) of the same group, , ; d. versus 6-OHDA, right side (R), , (two-tailed Student’s -test).