(a)
(b)
Figure 8: Representative photomicrographs (a) showing that valproic acid (VA) treatments (25 and 50 mg/kg) reverse the histone deacetylase (HDAC) immunoreactivities in CA1 and CA3 hippocampal areas and in the temporal cortex, TC. Scale bars represent 200 μm (magnification ×100). (b) Histograms showing relative optical densities measured by the Image J software. CA1: a. versus 6-OHDA, ; b. versus 6-OHDA + VA25, , . CA3: a. versus 6-OHDA, ; b. versus 6-OHDA, . TC: a. versus 6-OHDA, ; b. versus 6-OHDA, (one-way ANOVA and Newman-Keuls as the post hoc test and unpaired Student’s -test).