Disturbed Matrix Metalloproteinase Pathway in Both Age-Related Macular Degeneration and Alzheimer’s Disease

Figure 3

Effect of sample dilution on the release of bound MMPs. Supernatants from the undiluted and diluted brain homogenate (preparations A and B adjusted for dilution as described in the text) were subjected to zymographic analysis. Only the predominant pro-MMP9 species was detected but there was no significant difference in levels between preparations A and B. Lanes 1–3, preparation A. Lanes 4–6, preparation B.