Improved Methodology for Monitoring Poly(amidoamine) Dendrimers Surface Transformations and Product Quality by Ultra Performance Liquid Chromatography

Figure 1

HPLC chromatogram of (a) [EDA core], G = 5, amine terminated PAMAM dendrimers, (b) [EDA core], G = 4, amine terminated PAMAM dendrimers, and (c) [EDA core], G = 4, biotinylated PAMAM dendrimers. The concentrations of each dendrimer in solution are 0.75 mg/mL.