Improved Methodology for Monitoring Poly(amidoamine) Dendrimers Surface Transformations and Product Quality by Ultra Performance Liquid Chromatography

Figure 2

UPLC chromatogram of (a) [EDA core], G = 4, amine terminated PAMAM dendrimers, (b) [EDA core], G = 4, biotinylated PAMAMs and, (c) control blank of TFA. The concentrations of each dendrimer in solution are 0.50 mg/mL.