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Journal of Nanomaterials
Volume 2010, Article ID 818717, 7 pages
http://dx.doi.org/10.1155/2010/818717
Research Article

An Insight into the Interactions between -Tocopherol and Chitosan in Ultrasound-Prepared Nanoparticles

1Department of Medical Nanotechnology, Faculty of Advanced Medical Technologies, Tehran University of Medical Sciences, Tehran 14174, Iran
2Department of Pharmaceutical Biotechnology, Biotechnology Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, P.O. Box 14155-6451, Tehran 14174, Iran
3Biotechnology Research Center, Tehran University of Medical Sciences, Tehran 14174, Iran

Received 31 January 2010; Accepted 6 June 2010

Academic Editor: Doron Yadlovker

Copyright © 2010 Majid Naghibzadeh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. V. R. Sinha, A. K. Singla, S. Wadhawan et al., “Chitosan microspheres as a potential carrier for drugs,” International Journal of Pharmaceutics, vol. 274, no. 1-2, pp. 1–33, 2004. View at Publisher · View at Google Scholar · View at Scopus
  2. R. D. Bhumkar and V. B. Pokharkar, “Studies on effect of pH on cross-linking of chitosan with sodium tripolyphosphate: a technical note,” AAPS PharmSciTech, vol. 7, no. 2, article 50, 2006. View at Publisher · View at Google Scholar · View at Scopus
  3. G. Borchard, H. L. Lueßen, A. G. De Boer, J. C. Verhoef, C.-M. Lehr, and H. E. Junginger, “The potential of mucoadhesive polymers in enhancing intestinal peptide drug absorption. III: effects of chitosan-glutamate and carbomer on epithelial tight junctions in vitro,” Journal of Controlled Release, vol. 39, no. 2-3, pp. 131–138, 1996. View at Publisher · View at Google Scholar · View at Scopus
  4. S. Mansouri, P. Lavigne, K. Corsi, M. Benderdour, E. Beaumont, and J. C. Fernandes, “Chitosan-DNA nanoparticles as non-viral vectors in gene therapy: strategies to improve transfection efficacy,” European Journal of Pharmaceutics and Biopharmaceutics, vol. 57, no. 1, pp. 1–8, 2004. View at Publisher · View at Google Scholar · View at Scopus
  5. D.-G. Kim, C. Choi, Y.-I. Jeong et al., “All-trans retinoic acid-associated low molecular weight water-soluble chitosan nanoparticles based on ion complex,” Macromolecular Research, vol. 14, no. 1, pp. 66–72, 2006. View at Google Scholar · View at Scopus
  6. M. Lee, J.-W. Nah, Y. Kwon, J. J. Koh, K. S. Ko, and S. W. Kim, “Water-soluble and low molecular weight chitosan-based plasmid DNA delivery,” Pharmaceutical Research, vol. 18, no. 4, pp. 427–431, 2001. View at Publisher · View at Google Scholar · View at Scopus
  7. E. Reiter, Q. Jiang, and S. Christen, “Anti-inflammatory properties of α- and γ-tocopherol,” Molecular Aspects of Medicine, vol. 28, no. 5-6, pp. 668–691, 2007. View at Publisher · View at Google Scholar · View at Scopus
  8. J. K. Lodge, “Vitamin E bioavailability in humans,” Journal of Plant Physiology, vol. 162, no. 7, pp. 790–796, 2005. View at Publisher · View at Google Scholar · View at Scopus
  9. A. Dokoumetzidis and P. Macheras, “A century of dissolution research: from noyes and whitney to the biopharmaceutics classification system,” International Journal of Pharmaceutics, vol. 321, no. 1-2, pp. 1–11, 2006. View at Publisher · View at Google Scholar · View at Scopus
  10. T. Kotyla, F. Kuo, V. Moolchandani, T. Wilson, and R. Nicolosi, “Increased bioavailability of a transdermal application of a nano-sized emulsion preparation,” International Journal of Pharmaceutics, vol. 347, no. 1-2, pp. 144–148, 2008. View at Publisher · View at Google Scholar · View at Scopus
  11. P. B. Nielsen, A. Müllertz, T. Norling, and H. G. Kristensen, “The effect of α-tocopherol on the in vitro solubilisation of lipophilic drugs,” International Journal of Pharmaceutics, vol. 222, no. 2, pp. 217–224, 2001. View at Publisher · View at Google Scholar · View at Scopus
  12. A. Amani, P. York, H. Chrystyn, B. J. Clark, and D. Q. Do, “Determination of factors controlling the particle size in nanoemulsions using Artificial Neural Networks,” European Journal of Pharmaceutical Sciences, vol. 35, no. 1-2, pp. 42–51, 2008. View at Publisher · View at Google Scholar · View at Scopus
  13. M. L. Hans and A. M. Lowman, “Biodegradable nanoparticles for drug delivery and targeting,” Current Opinion in Solid State and Materials Science, vol. 6, no. 4, pp. 319–327, 2002. View at Publisher · View at Google Scholar · View at Scopus
  14. W. Klaypradit and Y.-W. Huang, “Fish oil encapsulation with chitosan using ultrasonic atomizer,” LWT—Food Science and Technology, vol. 41, no. 6, pp. 1133–1139, 2008. View at Publisher · View at Google Scholar · View at Scopus
  15. G. Ma, D. Yang, J. F. Kennedy, and J. Nie, “Synthesize and characterization of organic-soluble acylated chitosan,” Carbohydrate Polymers, vol. 75, no. 3, pp. 390–394, 2009. View at Publisher · View at Google Scholar · View at Scopus
  16. Y. B. Che Man, W. Ammawath, and M. E. S. Mirghani, “Determining α-tocopherol in refined bleached and deodorized palm olein by Fourier transform infrared spectroscopy,” Food Chemistry, vol. 90, no. 1-2, pp. 323–327, 2005. View at Publisher · View at Google Scholar · View at Scopus
  17. A. Lienau, T. Glaser, M. Krucker et al., “Qualitative and quantitative analysis of tocopherols in toothpastes and gingival tissue employing HPLC NMR and HPLC MS coupling,” Analytical Chemistry, vol. 74, no. 20, pp. 5192–5198, 2002. View at Publisher · View at Google Scholar · View at Scopus