105138.fig.004a
(a)
105138.fig.004b
(b)
Figure 4: The effect of a single base mismatch. (a) Real-time conductance change upon adding target DNA with an SNP (black curve) and target ssDNA with perfect match (orange). Inset shows an AFM image of the device used for the measurement. Scale bar; 1  m. (b) characteristics of the device at each functionalization and hybridization step.