Nano-Oncology: Clinical Application for Cancer Therapy and Future Perspectives

Table 1

Goals of targeted nanoscale drug delivery systems.

Characteristic of an ideal carrier for cancer therapy:
Biocompatible and biodegradable
Facilitate cellular uptake and intracellular trafficking
Retain the drug at the target site for the desired period of time
Protect the drug from the degradation and from premature
clereance
Ensure minimal drug leakage during transit to target
Decrease drug localisation in sensitive, non target tissue
Increase drug localisation in the tumour
(a) Passive targeting
(b) Active targeting