Preparation and Characterization of Water-Soluble Chitosan Microparticles Loaded with Insulin Using the Polyelectrolyte Complexation Method

Table 1

Effect of water-soluble chitosan (WSC) and TPP concentrations on the formation of microparticles.

WSC (mg/mL)	TPP (mg/mL)
	0.5	0.7	1.0	1.5	2.0
0.8	↓	↓	↓	↓	↓
1.0	∘	↓	↓	↓	↓
1.5	×	∘	↓	↓	↓
2.0	×	∘	∘	↓	↓
3.0	×	×	×	↓	↓

×: clear solution; ∘: opalescent suspension (nanoparticles); ↓: aggregation.