Dynamics of Spreading and Alignment of Cells Cultured In Vitro on a Grooved Polymer Surface

Figure 4

Time-lapse phase contrast images of a near-confluent CHO cell culture growing on a mechanically embossed polyester film. The dashed line denotes the border between an area with grooves (upper part of the images) and smooth control area (lower part of the images). Arrows denote cells which underwent mitosis. Scale bar, 20 𝜇m.