Research Article

Smart Magnetically Responsive Hydrogel Nanoparticles Prepared by a Novel Aerosol-Assisted Method for Biomedical and Drug Delivery Applications

Table 1

Different compositions and particle size of the developed magnetic hydrogel nanoparticles.

Formulation codePolymer aq. solution (2% w/v)Crosslinking fluidParticle size, (d, nm) ±SD
Alginate (w%)G-block (w%)CaCl2 (0.2 M)CaCl2/PEG-g-Cs (1 : 1)1Dry (DLS)2Dry (LM)2Swelled (LM)

IA10000936 ± 40852 ± 1451546 ± 84
IB10000926 ± 13811 ± 1051498 ± 102
IIA8020811 ± 162770 ± 1221571 ± 61
IIB8020929 ± 12794 ± 1771427 ± 179
IIIA7030941 ± 2855 ± 891640 ± 75
IIIB7030886 ± 2800 ± 1521592 ± 126

1Determined using DLS. 2Estimated using light microscopy (LM).