Journal of Nanomaterials / 2012 / Article / Tab 3 / Research Article
Formulation of LDL Targeted Nanostructured Lipid Carriers Loaded with Paclitaxel: A Detailed Study of Preparation, Freeze Drying Condition, and In Vitro Cytotoxicity Table 3 Physical properties of different NLCs.
Code Particle size (nm) Pd index Zeta potential (mV) EE* % DL** % Drug released after 72 h O15 P1 158.1 ± 17.1 0.1 ± 0.009 −20.8 ± 0.26 63 ± 13.2 3.3 ± 0.5 43.39 ± 6.8 O30 T2 80.68 ± 15.9 0.2 ± 0.01 −9.1 ± 0.12 72 ± 11.6 2.8 ± 0.3 53.9 ± 7.6 O30 P1 173.6 ± 19.8 0.3 ± 0.02 −12.7 ± 0.19 60 ± 10.3 2.8 ± 0.5 59.3 ± 5.6 O15 P2 132.9 ± 21.3 0.2 ± 0.04 −19.7 ± 0.23 63 ± 9.8 2.3 ± 0.4 52.23 ± 4.3 O15 T1 189.4 ± 15.6 0.6 ± 0.02 −9.17 ± 0.15 46 ± 10.2 2.1 ± 0.2 50.5 ± 8.5 O30 T1 100.9 ± 12.3 0.3 ± 0.01 −12.9 ± 0.15 62 ± 11.6 3.5 ± 0.2 50.23 ± 6.3 O30 P2 137.3 ± 13.4 0.1 ± 0.03 −8.8 ± 0.13 53 ± 8.6 2.9 ± 0.5 70.3 ± 5.4 O15 T2 169.8 ± 10.8 0.4 ± 0.04 −10.7 ± 0.09 53 ± 7.3 3.1 ± 0.6 63.78 ± 8.1
*EE: entrapment efficiency. **DL: drug loading.