Research Article

Changes in Cardiac Autonomic Regulation after Acute Lung Exposure to Carbon Nanotubes: Implications for Occupational Exposure

Table 1

Comparison of cardiovascular and autonomic values in baseline (i.e., before intratracheal instillation of either PBS or SWCNTs) condition between control and SWCNT instilled rats.

Control ( š‘› = 7 )Instilled ( š‘› = 9 )

SAP (mmHg) 1 3 0 . 7 Ā± 5 . 1 1 2 7 . 2 Ā± 5 . 0 NS
DAP (mmHg) 9 9 . 9 Ā± 4 . 4 9 5 . 8 Ā± 3 . 2 NS
HR (b/min) 3 3 3 . 1 Ā± 1 7 . 0 3 5 1 . 6 Ā± 1 2 . 0 NS
BARO% 8 . 3 Ā± 0 . 7 7 . 5 Ā± 0 . 5 NS
BRS (msec/mmHg) 4 . 1 Ā± 0 . 9 3 . 5 Ā± 0 . 6 NS
NBARO% 4 . 1 Ā± 0 . 5 3 . 9 Ā± 0 . 2 NS
NBRS (msec/mmHg) 4 . 1 Ā± 0 . 9 3 . 4 Ā± 0 . 5 NS

Mean values Ā± SEM. SAP: systolic arterial pressure; DAP: diastolic arterial pressure; HR: heart rate; BARO%: engagement time for baroreflex sequences; BRS: baroreflex sensitivity; NBARO%: engagement time for nonbaroreflex sequences; NBRS: gain of the nonbaroreflex sequences. Statiscal analysis has been performed by one-way repeated measures analysis of variance or Friedman repeated measures analysis of variance on ranks tests.