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Journal of Nanomaterials
Volume 2012, Article ID 720491, 12 pages
Research Article

Enhanced Visible-Light Photocatalytic Performance of Nanosized Anatase TiO2 Doped with CdS Quantum Dots for Cancer-Cell Treatment

1Laboratory of Quantum Information Technology, School of Physics and Telecommunication Engineering, South China Normal University, Guangzhou 510006, China
2School of Physics and Optoelectronic Engineering, Guangdong University of Technology, Guangzhou 510006, China
3Institute of Physics, Lanzhou University, Lanzhou 730107, China

Received 26 April 2012; Accepted 22 June 2012

Academic Editor: Jiaguo Yu

Copyright © 2012 Kangqiang Huang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


CdS quantum-dots-(QDs-)doped TiO2 nanocomposites were successfully synthesized using the sol-gel technique and characterized by SEM, TEM, XRD, EDS, UV-Vis, and FS. They were then used as a new “photosensitizer” based on photodynamic therapy (PDT) for cancer-cell treatment. The photocatalytic activities of CdS-TiO2 on leukemia tumors were investigated by using Cell Counting Kit-8 (CCK-8) assay. The ultrastructural morphology of treated cells was also studied by AFM. The experimental results indicated that an obvious inhibition of tumor growth would be observed in groups treated with CdS-TiO2 nanocomposites, and the PDT efficiency in the presence of CdS-doped TiO2 was significantly higher than that of TiO2, revealing that the photocatalytic activities of TiO2 could be effectively enhanced by the modification of CdS QDs. Additionally, CdS- TiO2 can exhibit a very high photodynamic efficiency of 80.5% at a final concentration of 200 μg/mL under visible-light irradiation. CdS-TiO2 nanocomposites in this case were regarded as a promising application for cancer-cell treatment.