Research Article

Self-Assembling Peptide Nanofiber Scaffold Enhanced with RhoA Inhibitor CT04 Improves Axonal Regrowth in the Transected Spinal Cord

Figure 3

Retrograde labeling of FG after SCI. (A, D, G, and J) shows the overviews of the FG-labeled spinal cord 13 weeks after treatments (rostral is to the left). (a, d, g, and j) are higher power magnification corresponding to boxed areas in (A, D, G, and J), respectively. The FG labeled neurons are in yellow. (B, E, H, K) and (C, F, I, L) show the FG-labeled neurons that appeared in the sensor-motor cortex (SMC) and red nuclei (RN) in different groups. (M) shows the quantification of FG-labeled neurons in the rostral spinal cord, indicating significant difference between SAPNS+CT04 and SAPNS with vehicle groups at 13 wks ( 𝑃 < 0 . 0 5 ).
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