Journal of Nanomaterials / 2012 / Article / Fig 4

Research Article

In Vitro Biocompatibility of Endodontic Sealers Incorporating Antibacterial Nanoparticles

Figure 4

The effect of AH+, Epiphany, and GuttaFlow endodontic sealers on the mitochondrial activity of the RAW macrophage cell line after 24 hrs immersion in media. Mitochondrial activity was normalized to the control without sealers stimulation. Stimulated macrophages (with heat-killed P. gingivalis) with and without the various endodontic sealers were immersed in media for 24 hrs and then transferred to cell cultured macrophages for another 24 hrs. Cell viability was tested using the XTT test. The results are expressed as the mean + SD. Statistically significant differences between the control (media) and the different groups are indicated by asterisks ( 𝑃 < 0 . 0 5 ) and 𝑛 = 8 wells.