Screening the Most Effective Variables on Physical Properties of Folate-Targeted Dextran/Retinoic Acid Micelles by Taguchi Design

Table 2

Composition of different formulations investigated in preparation of doxorubicin loaded in folate-targeted DEX/RA micelles of L₈ orthogonal array using Taguchi design.

Run	CMC (𝜇g/mL)	Polymer content (mg/100 mL)	DEX Mw	Stirring time (h)	Temperature (°C)	Stirring rate (rpm)	Drug concentration (%)
F1	>17	27	6000	1	50	400	30
F2	<17	27	10000	0.5	50	600	30
F3	>17	20	10000	0.5	40	400	30
F4	>17	27	6000	0.5	40	600	15
F5	<17	20	6000	1	40	600	30
F6	<17	27	10000	1	40	400	15
F7	<17	20	6000	0.5	50	400	15
F8	>17	20	10000	1	50	600	15