In Vitro Characterization of Pluronic F127 and D-𝜶-Tocopheryl Polyethylene Glycol 1000 Succinate Mixed Micelles as Nanocarriers for Targeted Anticancer-Drug Delivery

Table 1

Characterization of mixed micelles. The critical micelle concentration (CMC), size, zeta potential, drug loading content, and entrapment efficiency of mixed micelles. Data is represented as mean ± SD (𝑛=3), ^a = *𝑃<0.05, ^b = **𝑃<0.01 compared to 10 : 0 combination.

Sample	CMC (M)	Size (nm)	Zeta potential (mV)	DLC (%)	EE (%)
10 : 0	5 × 10^−4	22 ± 2.02	−10±0.58	1.5 ± 0.06	54 ± 2.6
7 : 3	5 × 10^−5	26 ± 1.32	−10±0.94	2.1 ± 0.23^b	72 ± 7.5^a
5 : 5	5 × 10^−5	35 ± 2.81^b	−13±1.50	2.8 ± 0.14^b	88 ± 7.4^b
3 : 7	5 × 10^−4	28 ± 1.20^a	−15±1.99^b	4.1 ± 0.13^b	69 ± 4.6^a