Research Article
Retinoic Acid Decorated Albumin-Chitosan Nanoparticles for Targeted Delivery of Doxorubicin Hydrochloride in Hepatocellular Carcinoma
Table 2
Composition of different formulations investigated in preparation of doxorubicin loaded in RC-albumin nanoparticles using irregular factorial design.
| Formulation code | Total mass of RC-albumin (mg) (A) | Albumin/RC (B) | Drug/RC-albumin (C) | Polymer type (D) |
| A100B1C0.5R2 | 100 | 1 | 0.5 | R2 | A10B0.5C0.5R2 | 10 | 0.5 | 0.5 | R2 | A10B0.5C0.25R2 | 10 | 0.5 | 0.25 | R2 | A100B0.5C0.5R4 | 100 | 0.5 | 0.5 | R4 | A100B0.5C0.5R2 | 100 | 0.5 | 0.5 | R2 | A10B1C0.5R2 | 10 | 1 | 0.5 | R2 | A100B1C0.25R2 | 100 | 1 | 0.25 | R2 | A100B0.5C0.25R4 | 100 | 0.5 | 0.25 | R4 | A10B1C0.5R4 | 10 | 1 | 0.5 | R4 | A100B1C0.25R4 | 100 | 1 | 0.25 | R4 | A10B0.5C0.25R4 | 10 | 0.5 | 0.25 | R4 | A10B1C0.25R4 | 10 | 1 | 0.25 | R4 |
|
|