The Development of Silicon Nanowire as Sensing Material and Its Applications
Figure 11
(a) Plots of normalized current change versus time with target DNA at a series of concentrations (0.1 fM, 1 fM, 10 fM, 1 pM, and 10 nM) for probe DNA modified SiNW device. Hybridization was demonstrated by 0.5 μM probe DNA functionalized SiNW biosensor in 0.01 × PBS. The length of all SiNWs was 6 μm. (b) Normalized current change as a function of the logarithm of target DNA concentration. (c) Plot of current versus time for unmodified SiNWs-FET, where region 1 stands for the presence of buffer solution and region 2 for the addition of 1 nM of fully target DNA. The error marks the point when the solution was changed. (d) Hybridization specificity demonstrated by 10 nM target DNAs. (Reprinted with permission from [93].)
