Bioreducible PEI-siRNA Nanocomplex for Liver Cancer Therapy: Transfection, Biodistribution, and Tumor Growth Inhibition In Vivo
Figure 1
(a) Chemical structure of bioreducible polyethylenimine (SS-PEI); (b) gel retardation assay on the binding of SS-PEI with plasmid gene; (c) and (d) dynamic light scattering analysis on the size, size distribution, and surface charge of SS-PEI/DNA complexes; (e) gel retardation assay on the binding of SS-PEI with VEGF-siRNA; (f) dynamic light scattering analysis on the size and surface charge of SS-PEI/siRNA complexes.