Novel Caffeic Acid Nanocarrier: Production, Characterization, and Release Modeling

Table 2

Kinetic parameters of caffeic acid release.

Nanocarrier	Zero order		First order		Higuchi		Ritger-Peppas			Reciprocal powered time			Weibull		Quadratic
	𝐾	𝑅	𝐾	𝑅	𝐾	𝑅	𝐾	𝑛	𝑅	𝐾	𝑎	𝑅	𝑎𝑤	𝑏𝑤	𝑅	𝐾1	𝐾2	𝑅
SLN	14.605	0.738	0.399	0.958	34.960	0.906	40.467	0.399	0.912	1.677	1.202	0.981	4.5 × 10^−5	0.105	0.508	−3.0 × 10^−4	3.3 × 10^−3	0.962
AL-CH coated SLN (0.1%)	7.606	0.721	0.112	0.790	18.550	0.908	23.848	0.328	0.960	3.821	0.663	0.982	4.1 × 10^−5	0.102	0.517	−1.6 × 10^−4	1.7 × 10^−3	0.918
AL-CH coated SLN (0.25%)	7.074	0.80	0.097	0.859	16.688	0.979	18.615	0.424	0.990	4.449	0.601	0.989	3.0 × 10^−5	0.102	0.511	−1.1 × 10^−4	1.4 × 10^−3	0.931
AL-CH coated SLN (0.5%)	8.478	0.762	0.129	0.844	20.214	0.956	23.908	0.382	0.983	3.772	0.539	0.995	1.8 × 10^−5	0.102	0.515	−1.5 × 10^−4	1.8 × 10^−3	0.933
PEC-CH coated SLN (0.1%)	5.723	0.763	0.073	0.814	13.445	0.944	15.460	0.402	0.957	5.585	0.537	0.967	4.6 × 10^−6	0.102	0.508	−1.0 × 10^−4	1.2 × 10^−3	0.957
PEC-CH coated SLN (0.25)	8.276	0.666	0.127	0.738	19.990	0.847	27.530	0.272	0.935	2.674	0.438	0.955	2.0 × 10^−5	0.102	0.518	−1.8 × 10^−4	1.9 × 10^−3	0.871
PEC-CH coated SLN (0.5%)	7.733	0.678	0.114	0.747	18.601	0.860	24.804	0.296	0.925	3.088	0.458	0.945	7.1 × 10^−6	0.102	0.515	−1.7 × 10^−4	1.8 × 10^−3	0.893