Obtaining of Sol-Gel Ketorolac-Silica Nanoparticles: Characterization and Drug Release Kinetics

Table 3

Drug release rates calculated for the different mathematical models.

Mathematical model	Ketorolac SiO2 1 : 4	Ketorolac SiO2 1 : 8
Zero-order [%/h]	30.51	0.09563
First-order [h]	3.057	0.00677
Higuchi [%]	72.97	1.69
Hixon-Crowell [h^−1]	0.5364	0.0081
Hyperbola [%/h]	176.62	88.01