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Journal of Nanomaterials
Volume 2013 (2013), Article ID 483569, 9 pages
http://dx.doi.org/10.1155/2013/483569
Research Article

Influence of Fe3O4 Nanoparticles on the Preparation of Aligned PLGA Electrospun Fibers Induced by Magnetic Field

Key Laboratory for Biomechanics and Mechanobiology of the Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, XueYuan Road No. 37, Haidian, Beijing 100191, China

Received 14 June 2013; Accepted 7 August 2013

Academic Editor: Xiaoming Li

Copyright © 2013 Ping Li et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The magnetic electrospinning (MES) method has been applied to generate aligned nanofibers. But researchers have different viewpoints on the usage of magnetic particles in the polymeric solutions. In order to investigate the effect of magnetic particles in forming the ordered fibers, the poly(lactic-co-glycolic acid) solutions with or without Fe3O4 nanoparticles were electrospun via MES. The fibers were compared at different voltages (13.5, 15.5, 17.5, and 19.5 kV) and flow rates (0.6, 0.9, 1.2, and 1.8 mL/h). It is shown that the well-aligned fibers can be fabricated by both magnetic and nonmagnetic solutions. The doping of Fe3O4 nanoparticles can increase the aligned fibers in some degree, especially at high applied voltage and flow rate. The diameters of fibers electrospun by MES were smaller than those by conventional electrospinning, and the diameter of fibers by MES without magnet particles was the smallest.