Preparation and Biological Properties of Platinum(II) Complex-Loaded Copolymer PLA-TPGS

Table 3

The cytotoxic activity of PLA-TPGS-Pt-thiomen on Hep-G2 cells.

Number	Concentration (µg/mL)	Cell line Hep-G2
		Survival (%)	IC50 (µg/mL)
1	Ellipticine (reference)	0.32±0.04	0.27
2	Pt-thiomen
	20	25±0.9	13.6
	10	38±0.2
	5	80±0.1
	2.5	91±0.5
3	PLA-TPGS
	100	90±0.7	ND
4	PLA-TPGS-Pt-thiomen
	20	6.8±0.7	5.05
	10	20.6±0.3
	5	42.5±0.9
	2.5	73.8±1.1
	1.25	91.3±0.8

ND: not detectable.