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Journal of Nanomaterials
Volume 2013, Article ID 808234, 8 pages
http://dx.doi.org/10.1155/2013/808234
Review Article

Nanotechnological Advances in Cutaneous Medicine

Centre for Regenerative Medicine, Mawson Institute, Division of ITEE, University of South Australia, Mawson Lakes, Adelaide SA5095, Australia

Received 4 September 2013; Accepted 27 October 2013

Academic Editor: Krasimir Vasilev

Copyright © 2013 Jessica E. Jackson et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Wound healing is an area of unmet clinical need. Current treatments include occlusive dressings, hydrogels, and antimicrobials to control infection. However with the growing number of antibiotic-resistant bacteria and the increase in population age and clinical obesity, it is becoming proportionally harder to treat wounds with the drugs that have worked in the past. There is an urgent requirement for efficient mechanism-based treatments and more efficacious drug delivery systems. The potential of using nanoparticles as a drug delivery system has been identified and investigated. Nanoparticles have the ability to protect and carry drugs to specific targets in the body, enabling slower degradation, enhancing drug penetration, improving treatment efficacy with lower systemic absorption, and reducing unwanted side effects. Here we discuss the advantages and limitations of nanotechnology for the treatment of wounds and other cutaneous disorders.