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Journal of Nanomaterials
Volume 2013, Article ID 865024, 8 pages
http://dx.doi.org/10.1155/2013/865024
Research Article

Cytotoxic Effect of Nanocrystalline MgFe2O4 Particles for Cancer Cure

1Materials Synthesis and Characterization Laboratory (MSCL), Institute of Advanced Technology (ITMA), Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia
2Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia

Received 30 August 2013; Accepted 16 October 2013

Academic Editor: William W. Yu

Copyright © 2013 S. Kanagesan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. Hu, T. W. Odom, and C. M. Lieber, “Chemistry and physics in one dimension: synthesis and properties of nanowires and nanotubes,” Accounts of Chemical Research, vol. 32, no. 5, pp. 435–445, 1999. View at Publisher · View at Google Scholar · View at Scopus
  2. Z. L. Wang, Y. Liu, and Z. Zhang, Handbook of Nanophase and Nanostructured Materials, vol. 3, Kluwer Academic/Plenum, New York, NY, USA, 2003.
  3. R. J. Willey, P. Noirclerc, and G. Busca, “Preparation and characterization of magnesium chromite and magnesium ferrite aerogels,” Chemical Engineering Communications, vol. 123, pp. 1–16, 1993. View at Google Scholar · View at Scopus
  4. N. Sivakumar, A. Narayanasamy, J.-M. Greneche, R. Murugaraj, and Y. S. Lee, “Electrical and magnetic behaviour of nanostructured MgFe2O4 spinel ferrite,” Journal of Alloys and Compounds, vol. 504, no. 2, pp. 395–402, 2010. View at Publisher · View at Google Scholar · View at Scopus
  5. H. Deng, H. Chen, and H. Li, “Synthesis of crystal MFe2O4 (M = Mg, Cu, Ni) microspheres,” Materials Chemistry and Physics, vol. 101, no. 2-3, pp. 509–513, 2007. View at Publisher · View at Google Scholar · View at Scopus
  6. S.-H. Yu and M. Yoshimura, “Direct fabrication of ferrite MFe2O4 (M = Zn, Mg)/Fe composite thin films by soft solution processing,” Chemistry of Materials, vol. 12, no. 12, pp. 3805–3810, 2000. View at Publisher · View at Google Scholar · View at Scopus
  7. J. Rockenberger, E. C. Scher, and A. P. Alivisatos, “A new nonhydrolytic single-precursor approach to surfactant-capped nanocrystals of transition metal oxides,” Journal of the American Chemical Society, vol. 121, no. 49, pp. 11595–11596, 1999. View at Publisher · View at Google Scholar · View at Scopus
  8. T. Hyeon, “Chemical synthesis of magnetic nanoparticles,” Chemical Communications, vol. 9, no. 8, pp. 927–934, 2003. View at Google Scholar · View at Scopus
  9. N. R. Jana, Y. Chen, and X. Peng, “Size- and shape-controlled magnetic (Cr, Mn, Fe, Co, Ni) oxide nanocrystals via a simple and general approach,” Chemistry of Materials, vol. 16, no. 20, pp. 3931–3935, 2004. View at Publisher · View at Google Scholar · View at Scopus
  10. S. Komarneni, E. Fregeau, E. Breval, and R. Roy, “Hydrothermal preparation of ultrafine ferrites and their sintering,” Journal of the American Ceramic Society, vol. 71, p. C-26, 1998. View at Google Scholar
  11. Q. Chen, A. J. Rondinone, B. C. Chakoumakos, and Z. John Zhang, “Synthesis of superparamagnetic MgFe2O4 nanoparticles by coprecipitation,” Journal of Magnetism and Magnetic Materials, vol. 194, no. 1, pp. 1–7, 1999. View at Publisher · View at Google Scholar · View at Scopus
  12. K. Suresh, N. R. S. Kumar, and K. C. Patil, “A novel combustion synthesis of spinel ferrites, orthoferrites and garnets,” Advanced Materials, vol. 3, no. 3, pp. 148–150, 1991. View at Google Scholar · View at Scopus
  13. A. S. Albuquerque, J. D. Ardisson, and W. A. A. Macedo, “A study of nanocrystalline NiZn-ferrite-SiO2 synthesized by sol-gel,” Journal of Magnetism and Magnetic Materials, vol. 192, no. 2, pp. 277–280, 1999. View at Publisher · View at Google Scholar
  14. N. S. Gajbhiye, S. Prasad, and G. Balaji, “Experimental study of hopkinson effect in single domain CoFe2U4 particles,” IEEE Transactions on Magnetics, vol. 35, no. 4, pp. 2155–2161, 1999. View at Publisher · View at Google Scholar · View at Scopus
  15. H. F. Yu and A. M. Gadalla, “Preparation of NiFe2O4 powder by spray pyrolysis of nitrate aerosols in NH3,” Journal of Materials Research, vol. 11, no. 3, pp. 663–670, 1996. View at Publisher · View at Google Scholar
  16. N. Moumen and M. P. Pileni, “Control of the size of cobalt ferrite magnetic fluid,” Journal of Physical Chemistry, vol. 100, no. 5, pp. 1867–1873, 1996. View at Google Scholar · View at Scopus
  17. C. Liu, B. Zou, A. J. Rondinone, and Z. J. Zhang, “Chemical control of superparamagnetic properties of magnesium and cobalt spinel ferrite nanoparticles through atomic level magnetic couplings,” Journal of the American Chemical Society, vol. 122, no. 26, pp. 6263–6267, 2000. View at Publisher · View at Google Scholar · View at Scopus
  18. Q. A. Pankhurst, J. Connolly, S. K. Jones, and J. Dobson, “Applications of magnetic nanoparticles in biomedicine,” Journal of Physics D, vol. 36, no. 13, pp. R167–R181, 2003. View at Publisher · View at Google Scholar · View at Scopus
  19. J. Huang, H. Li, W. Chen et al., “Dielectric barrier discharge plasma in Ar/O2 promoting apoptosis behavior in A549 cancer cells,” Applied Physics Letters, vol. 99, no. 25, Article ID 253701, 2011. View at Publisher · View at Google Scholar · View at Scopus
  20. K. Karthikeyan, A. Babu, S.-J. Kim, R. Murugesan, and K. Jeyasubramanian, “Enhanced photodynamic efficacy and efficient delivery of Rose Bengal using nanostructured poly(amidoamine) dendrimers: potential application in photodynamic therapy of cancer,” Cancer Nanotechnology, vol. 2, no. 1–6, pp. 95–103, 2011. View at Publisher · View at Google Scholar · View at Scopus
  21. J. L. Arias, L. H. Reddy, and P. Couvreur, “Fe3O4/chitosan nanocomposite for magnetic drug targeting to cancer,” Journal of Materials Chemistry, vol. 22, no. 15, pp. 7622–7632, 2012. View at Publisher · View at Google Scholar · View at Scopus
  22. N. K. Singh, S. K. Singh, D. Dash, B. P. Purkayastha, J. K. Roy, and P. Maiti, “Nanostructure controlled anti-cancer drug delivery using poly(ε-caprolactone) based nanohybrids,” Journal of Materials Chemistry, vol. 22, pp. 17853–1763, 2012. View at Publisher · View at Google Scholar
  23. M. Premanathan, K. Karthikeyan, K. Jeyasubramanian, and G. Manivannan, “Selective toxicity of ZnO nanoparticles toward Gram-positive bacteria and cancer cells by apoptosis through lipid peroxidation,” Nanomedicine, vol. 7, no. 2, pp. 184–192, 2011. View at Publisher · View at Google Scholar · View at Scopus
  24. P. Sanpui, A. Chattopadhyay, and S. S. Ghosh, “Induction of apoptosis in cancer cells at low silver nanoparticle concentrations using chitosan nanocarrier,” ACS Applied Materials and Interfaces, vol. 3, no. 2, pp. 218–228, 2011. View at Publisher · View at Google Scholar · View at Scopus
  25. C. R. Patra, R. Bhattacharya, and P. Mukherjee, “Fabrication and functional characterization of goldnanoconjugates for potential application in ovarian cancer,” Journal of Materials Chemistry, vol. 20, no. 3, pp. 547–554, 2010. View at Publisher · View at Google Scholar · View at Scopus
  26. K. M. Reddy, K. Feris, J. Bell, D. G. Wingett, C. Hanley, and A. Punnoose, “Selective toxicity of zinc oxide nanoparticles to prokaryotic and eukaryotic systems,” Applied Physics Letters, vol. 90, no. 21, Article ID 213902, 2007. View at Publisher · View at Google Scholar · View at Scopus
  27. A. Niu, Y. Han, J. Wu, N. Yu, and Q. Xu, “Synthesis of one-dimensional carbon nanomaterials wrapped by silver nanoparticles and their antibacterial behavior,” The Journal of Physical Chemistry C, vol. 114, pp. 12728–1235, 2010. View at Publisher · View at Google Scholar
  28. W. Zhou, X. Liu, and J. Ji, “Fast and selective cancer cell uptake of therapeutic gold nanorods by surface modifications with phosphorylcholine and Tat,” Journal of Materials Chemistry, vol. 22, pp. 13969–13976, 2012. View at Publisher · View at Google Scholar
  29. M. Ahamed, M. J. Akhtar, M. Raja et al., “ZnO nanorod-induced apoptosis in human alveolar adenocarcinoma cells via p53, survivin and bax/bcl-2 pathways: role of oxidative stress,” Nanomedicine, vol. 7, no. 6, pp. 904–913, 2011. View at Publisher · View at Google Scholar · View at Scopus
  30. P. Thevenot, J. Cho, D. Wavhal, R. B. Timmons, and L. Tang, “Surface chemistry influences cancer killing effect of TiO2 nanoparticles,” Nanomedicine, vol. 4, no. 3, pp. 226–236, 2008. View at Publisher · View at Google Scholar · View at Scopus
  31. S. Makhluf, R. Dror, Y. Nitzan, Y. Abramovich, R. Jelinek, and A. Gedanken, “Microwave-assisted synthesis of nanocrystalline MgO and its use as a bacteriocide,” Advanced Functional Materials, vol. 15, no. 10, pp. 1708–1715, 2005. View at Publisher · View at Google Scholar · View at Scopus
  32. K. Krishnamoorthy, G. Manivannan, S. J. Kim, K. Jeyasubramanian, and M. Premanathan J, “Antibacterial activity of MgO nanoparticles based on lipid peroxidation by oxygen vacancy,” Journal of Nanoparticle Research, vol. 14, no. 1063, 2012. View at Publisher · View at Google Scholar
  33. S. Ge, G. Wang, Y. Shen et al., “Cytotoxic effects of MgO nanoparticles on human umbilical vein endothelial cells in vitro,” IET Nanobiotechnology, vol. 5, no. 2, pp. 36–40, 2011. View at Publisher · View at Google Scholar · View at Scopus
  34. J. Sun, S. Wang, D. Zhao, F. H. Hun, L. Weng, and H. Liu, “Cytotoxicity, permeability, and inflammation of metal oxide nanoparticles in human cardiac microvascular endothelial cells,” Cell Biology and Toxicology, vol. 27, no. 5, pp. 333–42, 2011. View at Publisher · View at Google Scholar
  35. J. C. K. Lai, M. B. Lai, S. Jandhyam et al., “Exposure to titanium dioxide and other metallic oxide nanoparticles induces cytotoxicity on human neural cells and fibroblasts,” International Journal of Nanomedicine, vol. 3, no. 4, pp. 533–545, 2008. View at Google Scholar · View at Scopus
  36. D. R. Di, Z. Z. He, Z. Q. Sun, and J. Liu, “A new nano-cryosurgical modality for tumor treatment using biodegradable MgO nanoparticles,” Nanomedicine, vol. 8, no. 8, pp. 1233–141.
  37. G. Bahmanrokha, M. Hashima, N. Soltani et al., “High coercivity sized controlled cobalt-gold core-shell nano-crystals prepared by reverse microemulsion,” Materials Research Bulletin, vol. 48, no. 10, pp. 4039–4047, 2013. View at Publisher · View at Google Scholar
  38. S. Kanagesan, S. Jesurani, R. Velmurugan, M. Sivakumar, C. Thirupathi, and T. Kalaivani, “Synthesis and magnetic properties of conventional and microwave calcined barium hexaferrite powder,” Journal of Materials Science, vol. 23, no. 2, pp. 635–639, 2012. View at Publisher · View at Google Scholar · View at Scopus
  39. C.-Y. Zhang, X.-Q. Shen, J.-X. Zhou, M.-X. Jing, and K. Cao, “Preparation of spinel ferrite NiFe2O4 fibres by organic gel-thermal decomposition process,” Journal of Sol-Gel Science and Technology, vol. 42, no. 1, pp. 95–100, 2007. View at Publisher · View at Google Scholar · View at Scopus
  40. P. Sivakumar, R. Ramesh, A. Ramanand, S. Ponnusamy, and C. Muthamizhchelvan, “Synthesis, studies and growth mechanism of ferromagnetic NiFe2O4 nanosheet,” Applied Surface Science, vol. 258, no. 17, pp. 6648–6652, 2012. View at Publisher · View at Google Scholar · View at Scopus
  41. S. Zahi, “Nickel-zinc ferrite fabricated by sol-gel route and application in high-temperature superconducting magnetic energy storage for voltage sag solving,” Materials and Design, vol. 31, no. 4, pp. 1848–1853, 2010. View at Publisher · View at Google Scholar · View at Scopus
  42. P. Sivakumar, R. Ramesh, A. Ramanand, S. Ponnusamy, and C. Muthamizhchelvan, “Synthesis and study of magnetic properties of NiFe2O4 nanoparticles by PVA assisted auto-combustion method,” Journal of Materials Science, vol. 23, pp. 1011–1015, 2012. View at Publisher · View at Google Scholar · View at Scopus
  43. J. Chandradass, A. H. Jadhav, K. H. Kim, and H. Kim, “Influence of processing methodology on the structural and magnetic behavior of MgFe2O4 nanopowders,” Journal of Alloys and Compounds, vol. 517, pp. 164–169, 2012. View at Publisher · View at Google Scholar · View at Scopus
  44. S. Thankachan, S. Xavier, B. Jacob, and E. M. Mohammed, “A comparative study of structural, electrical and magnetic properties of magnesium ferrite nanoparticles synthesised by sol-gel and co-precipitation techniques,” Journal of Experimental Nanoscience:, vol. 8, no. 3, pp. 347–357, 2013. View at Publisher · View at Google Scholar
  45. A. N. Pathan, K. Sangshetti, and A. A. G. Pangal, “Synthesis, Characterisation and magnetic studies of Co0.6Zn0.4-xCuxFe2O4 Nanoparticles,” International of Journal Nanotechnology & Nanosciences, vol. 1, pp. 8–12, 2010. View at Google Scholar
  46. M. Y. Salunkhe, D. S. Choudhary, and D. K. Kulkarni, “Infrared absorption studies of the system Sr2Me2Fe12O22,” Vibrational Spectroscopy, vol. 34, no. 2, pp. 221–224, 2004. View at Publisher · View at Google Scholar · View at Scopus
  47. V. A. Potakova, N. D. Zverv, and V. P. Romanov, “On the cation distribution in Ni1xyFex2+ZnyFe23+ spinel ferrites,” Physica Status Solidi A, vol. 12, no. 2, pp. 623–627, 1972. View at Publisher · View at Google Scholar
  48. J. Chandradass, A. H. Jadhav, K. H. Kim, and H. Kim, “Influence of processing methodology on the structural and magnetic behavior of MgFe2O4 nanopowders,” Journal of Alloys and Compounds, vol. 517, pp. 164–169, 2012. View at Publisher · View at Google Scholar · View at Scopus
  49. Y. Ahn, E. J. Choi, and E. H. Kim, “Superparamagnetic relaxation in cobalt ferrite nanoparticles synthesized from hydroxide carbonate precursors,” Reviews on Advanced Materials Science, vol. 5, p. 477, 2003. View at Google Scholar
  50. N. Wu, L. Fu, M. Su, M. Aslam, K. C. Wong, and V. P. Dravid, “Interaction of fatty acid monolayers with cobalt nanoparticles,” Nano Letters, vol. 4, no. 2, pp. 383–386, 2004. View at Publisher · View at Google Scholar · View at Scopus
  51. H. Stablein and E. P. Wohlfarth, Eds., Ferromagnetic Materials, 3 North-Holland, 1982.
  52. J. Smit and H. P. J. Wijn, Ferrites Physical Properties of Ferromagnetic Oxides in Relation To Their Technical Applications, Wiley, New York, NY, USA, 1959.
  53. P. Sivakumar, R. Ramesh, A. Ramanand, S. Ponnusamy, and C. Muthamizhchelvan, “Preparation of sheet like polycrystalline NiFe2O4 nanostructure with PVA matrices and their properties,” Materials Letters, vol. 65, no. 9, pp. 1438–1440, 2011. View at Publisher · View at Google Scholar · View at Scopus
  54. A. Pradeep, P. Priyadharsini, and G. Chandrasekaran, “Sol- gel route of synthesis of nanoparticles of MgFe2O4 and XRD, FTIR and VSM study,” Journal of Magnetism and Magnetic Materials, vol. 320, no. 21, pp. 2774–2779, 2008. View at Publisher · View at Google Scholar · View at Scopus
  55. G.-F. Yang, X.-H. Li, Z. Zhao, and W.-B. Wang, “Preparation, characterization, in vivo and in vitro studies of arsenic trioxide Mg-Fe ferrite magnetic nanoparticles,” Acta Pharmacologica Sinica, vol. 30, no. 12, pp. 1688–1693, 2009. View at Publisher · View at Google Scholar · View at Scopus
  56. T. T. Mai, J. Moon, Y. Song et al., “Ginsenoside F2 induces apoptosis accompanied by protective autophagy in breast cancer stem cells,” Cancer Letters, vol. 321, no. 2, pp. 144–153, 2012. View at Publisher · View at Google Scholar · View at Scopus
  57. S. J. Martin, C. P. M. Reutelingsperger, A. J. McGahon et al., “Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl,” Journal of Experimental Medicine, vol. 182, no. 5, pp. 1545–1556, 1995. View at Publisher · View at Google Scholar · View at Scopus
  58. G. Koopman, C. P. M. Reutelingsperger, G. A. M. Kuijten, R. M. J. Keehnen, S. T. Pals, and M. H. J. Van Oers, “Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis,” Blood, vol. 84, no. 5, pp. 1415–1420, 1994. View at Google Scholar · View at Scopus
  59. N. Ueda and S. V. Shah, “Apoptosis,” Journal of Laboratory and Clinical Medicine, vol. 124, no. 2, pp. 169–177, 1994. View at Google Scholar · View at Scopus
  60. M. Symons and J. Gutteridge, Free Radicals and Iron: Chemistry, Biology and Medicine, Oxford University Press, London, UK, 1998.