Research Article

Hyaluronate Targeted Solid Lipid Nanoparticles of Etoposide: Optimization and In Vitro Characterization

Table 5

Etoposide loading and release efficiency percent in 24 hours from HA targeted SLNs ( ).

Formulation codeLoading efficiency (%)RE24 (%)

C2L1.5DO2054.76 ± 5.7152.89 ± 7.06
C1L3SO2059.76 ± 3.2265.05 ± 4.11
C1L3DO2042.56 ± 6.3259.71 ± 8.17
C2L3DO1058.31 ± 8.7957.49 ± 6.92
C1L3SO1065.70 ± 5.3669.06 ± 5.62
C1L1.5SO1066.58 ± 4.5665.36 ± 4.53
C1L1.5DO2039.53 ± 7.1655.22 ± 7.86
C2L1.5SO2037.84 ± 6.1954.47 ± 7.26
C1L1.5DO1040.66 ± 5.5259.71 ± 6.44
C2L3DO2053.55 ± 8.4954.24 ± 7.39
C2L3SO1043.72 ± 8.2759.28 ± 6.83
C2L1.5SO1041.93 ± 4.9555.35 ± 5.92