Impact of Silver and Iron Nanoparticle Exposure on Cholesterol Uptake by Macrophages

Figure 3

Cell viability changes in macrophages following exposure to 20 nm AgNPs, 110 nm AgNPs, or 20 nm Fe₃O₄ NPs at 6.25, 12.5, 25, or 50 μg/mL for (a) 2 h or (b) 24 h. (c) Alterations in cell viability following a 2 h exposure to 20 nm AgNPs, 110 nm AgNPs, or 20 nm Fe₃O₄ NPs (25 μg/mL) and a subsequent 24 h treatment to either serum-free media or serum-free media containing cholesterol (20 μg/mL). (d) Cell viability following a 24 h exposure to 20 nm AgNPs, 110 nm AgNPs, or 20 nm Fe₃O₄ NPs (25 μg/mL) in either serum-free media or serum-free media containing cholesterol (20 μg/mL). Values are expressed as mean ± SEM (/group). indicates significant difference from controls (untreated) ().

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