Comparison of the Effect of Sol-Gel and Coprecipitation Routes on the Properties and Behavior of Nanocomposite Chitosan-Bioactive Glass Membranes for Bone Tissue Engineering

<div>Cell viability of hybrid CS-BG and the CS-BGNP nanocomposites. <svg height="13.9756pt" id="M8" style="vertical-align:-3.7426pt" version="1.1" viewbox="-0.0498162 -10.233 6.17869 13.9756" width="6.17869pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0091,0,0,-0.0091,0,-5.872)"><path d="M486 158C486 177 478 202 466 220C413 228 386 236 336 262C386 288 413 297 466 304C478 323 486 347 485 366C470 376 444 381 422 380C389 338 368 319 321 288C323 345 329 372 349 422C339 442 322 461 305 470C289 461 271 442 262 422C281 372 287 345 290 288C243 319 222 338 189 380C167 381 142 376 125 366C125 347 133 322 145 304C198 296 225 288 275 262C225 236 198 227 145 220C133 201 125 177 126 158C141 148 167 143 189 144C222 186 243 205 290 236C288 179 282 152 262 102C272 82 289 63 306 54C322 63 340 82 350 102C330 152 324 179 321 236C368 205 390 186 422 144C444 143 470 148 486 158Z" id="g50-43"></path><glyph.data ascent="3443" descent="-2856" horiz-adv-x="611" vert-adv-y="611"></glyph.data></g></svg>Statistically significant difference (<svg height="9.29899pt" id="M9" style="vertical-align:-0.7022505pt" version="1.1" viewbox="-0.0498162 -8.59674 45.6962 9.29899" width="45.6962pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M622 479C622 589 545 650 400 650H146L140 618C229 609 230 602 215 527L135 132C117 43 112 41 27 32L18 0H305L313 32C213 40 205 44 222 132L251 284L324 262H365C484 269 622 333 622 479ZM528 477C528 356 420 305 344 305C300 305 276 314 259 321L303 554C311 597 313 600 331 606C345 611 361 614 379 614C463 614 528 580 528 477Z" id="g50-81"></path><glyph.data ascent="3443" descent="-2856" horiz-adv-x="640" vert-adv-y="640"></glyph.data></g><g transform="matrix(.013,0,0,-0.013,11.766,0)"><path d="M530 -6V57L144 261V263L530 468V530L81 290V234L530 -6Z" id="g54-91"></path><glyph.data ascent="3443" descent="-2856" horiz-adv-x="611" vert-adv-y="611"></glyph.data></g><g transform="matrix(.013,0,0,-0.013,23.385,0)"><path d="M245 635C92 635 37 457 37 312C37 148 92 -12 244 -12C395 -12 449 165 449 312C449 469 394 635 245 635ZM243 598C332 598 358 454 358 312C358 172 334 26 245 26C158 26 128 174 128 313S151 598 243 598Z" id="g58-46"></path><glyph.data ascent="1007" descent="-369" horiz-adv-x="487" vert-adv-y="487"></glyph.data></g><g transform="matrix(.013,0,0,-0.013,29.716,0)"><path d="M117 -12C153 -12 178 12 178 50C178 84 153 110 118 110C84 110 59 84 59 50C59 12 84 -12 117 -12Z" id="g50-47"></path><glyph.data ascent="3443" descent="-2856" horiz-adv-x="237" vert-adv-y="237"></glyph.data></g><g transform="matrix(.013,0,0,-0.013,32.797,0)"><path d="M245 635C92 635 37 457 37 312C37 148 92 -12 244 -12C395 -12 449 165 449 312C449 469 394 635 245 635ZM243 598C332 598 358 454 358 312C358 172 334 26 245 26C158 26 128 174 128 313S151 598 243 598Z" id="g58-46"></path><glyph.data ascent="1007" descent="-369" horiz-adv-x="487" vert-adv-y="487"></glyph.data></g><g transform="matrix(.013,0,0,-0.013,39.128,0)"><path d="M158 548H390L417 615L410 623H122L83 318C106 326 142 337 185 337C296 337 350 275 350 188C350 116 308 42 225 42C165 42 121 74 100 93C89 101 83 99 72 92C60 81 51 68 50 59C47 46 51 39 66 24C82 9 125 -12 172 -12C225 -11 291 15 346 59C409 108 437 166 437 226C437 309 370 397 242 397C214 397 170 382 133 369L158 548Z" id="g58-51"></path><glyph.data ascent="1007" descent="-369" horiz-adv-x="487" vert-adv-y="487"></glyph.data></g></svg>). Statistical analysis performed by ANOVA/Bonferroni/GraphPad Prism.</div>

Journal of Nanomaterials

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Figure 4

Figure 4: Comparison of the Effect of Sol-Gel and Coprecipitation Routes on the Properties and Behavior of Nanocomposite Chitosan-Bioactive Glass Membranes for Bone Tissue Engineering 

Figure 4 | Comparison of the Effect of Sol-Gel and Coprecipitation Routes on the Properties and Behavior of Nanocomposite Chitosan-Bioactive Glass Membranes for Bone Tissue Engineering 