Applications of Thermoresponsive Magnetic Nanoparticles

Table 1

Thermoresponsive polymer-magnetic nanoparticle composites for drug delivery and imaging application.

Magnetic core-size (diameter-TEM)	Polymer	LCST	Application	Reference
-50 nm	Poly(N,N′-isopropylacrylamide-co-N-hydroxymethylacrylamide) (P(NIPAAm-co-HMAAm))	40°C	In vitro hyperthermia	[39]
Fe3O4-Au-115 nm	PNIPAAm	32°C	Surface plasmon resonance (SPR) based heating	[40]
Fe3O4-8 nm	Dextran grafted poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide) [dextran-g-poly(NIPAAm-co-DMAAm)]	38°C	Not reported	[41]
Fe3O4-12 nm	PNIPAAm	40°C	In vitro drug delivery, magnetic heating	[42]
γ-Fe2O3-7.5 nm	Poly(vinyl alcohol)-b-poly(N-vinylcaprolactam); (PVOH-b-PNVCL)	41°C	In vitro drug delivery, magnetic heating	[43]
Fe3O4-13 nm	Poly(N,N′-isopropylacrylamide-co-styrene) (P(NIPAAm-co-St))	27–35°C	In vivo MRI	[44]
Fe3O4-SiO2-80 nm	Poly(N,N′-isopropylacrylamide)-block-polystyrene (PNIPAAm-b-PSt)	32°C	In vitro MRI	[45]