Table of Contents Author Guidelines Submit a Manuscript
Journal of Nanomaterials
Volume 2015, Article ID 374218, 8 pages
http://dx.doi.org/10.1155/2015/374218
Research Article

In Silico Study of Spacer Arm Length Influence on Drug Vectorization by Fullerene C60

1Research Unity of Modeling in Fundamental Sciences and Didactics, Université de Tunis El Manar, IPEIEM, BP 254, El Manar 2, 2096 Tunis, Tunisia
2LETIAM, Lip(Sys)2, University of Paris Sud, IUT d’Orsay, Plateau de Moulon, 91400 Orsay, France

Received 12 January 2015; Revised 9 May 2015; Accepted 10 May 2015

Academic Editor: Miguel A. Correa-Duarte

Copyright © 2015 Haifa Khemir et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. Davies, “Inactivation of antibiotics and the dissemination of resistance genes,” Science, vol. 264, no. 5157, pp. 375–382, 1994. View at Publisher · View at Google Scholar · View at Scopus
  2. H. W. Kroto, J. R. Heath, S. C. O'Brien, R. F. Curl, and R. E. Smalley, “C60: buckminsterfullerene,” Nature, vol. 318, no. 6042, pp. 162–163, 1985. View at Publisher · View at Google Scholar · View at Scopus
  3. A. W. Jensen, S. R. Wilson, and D. I. Schuster, “Biological applications of fullerenes,” Bioorganic and Medicinal Chemistry, vol. 4, no. 6, pp. 767–779, 1996. View at Publisher · View at Google Scholar · View at Scopus
  4. H. Szwarc and F. Moussa, “[60] Fullerene and derivatives in biology and medicine,” in Handbook of Fullerene: Synthesis, Properties and Applications, R. F. Verner and C. Benvegn, Eds., pp. 403–420, Nova Science Publishers, New York, NY, USA, 2012. View at Google Scholar
  5. J. Kolosnjaj, H. Szwarc, and F. Moussa, “Toxicity studies of fullerenes and derivatives,” Advances in Experimental Medicine and Biology, vol. 620, pp. 168–180, 2007. View at Publisher · View at Google Scholar · View at Scopus
  6. R. Maeda-Mamiya, E. Noiri, H. Isobe et al., “In vivo gene delivery by cationic tetraamino fullerene,” Proceedings of the National Academy of Sciences of the United States of America, vol. 107, no. 12, pp. 5339–5344, 2010. View at Publisher · View at Google Scholar · View at Scopus
  7. K. L. Quick, S. S. Ali, R. Arch, C. Xiong, D. Wozniak, and L. L. Dugan, “A carboxyfullerene SOD mimetic improves cognition and extends the lifespan of mice,” Neurobiology of Aging, vol. 29, no. 1, pp. 117–128, 2008. View at Publisher · View at Google Scholar · View at Scopus
  8. J. Gao, Y. Wang, K. M. Folta et al., “Polyhydroxy fullerenes (fullerols or fullerenols): beneficial effects on growth and lifespan in diverse biological models,” PLoS ONE, vol. 6, no. 5, Article ID e19976, 2011. View at Publisher · View at Google Scholar · View at Scopus
  9. T. Baati, F. Bourasset, N. Gharbi et al., “The prolongation of the lifespan of rats by repeated oral administration of [60]fullerene,” Biomaterials, vol. 33, no. 19, pp. 4936–4946, 2012. View at Publisher · View at Google Scholar · View at Scopus
  10. M. S. Butt and M. T. Sultan, “Nigella sativa: reduces the risk of various maladies,” Critical Reviews in Food Science and Nutrition, vol. 50, no. 7, pp. 654–665, 2010. View at Publisher · View at Google Scholar · View at Scopus
  11. N. Ilaiyaraja and F. Khanum, “Nigella sativa L.: a review of therapeutic application,” Journal of Herbal Medicine and Toxicology, vol. 4, pp. 1–8, 2010. View at Google Scholar
  12. S. Padhye, S. Banerjee, A. Ahmad, R. Mohammad, and F. H. Sarkar, “From here to eternity—the secret of Pharaohs: therapeutic potential of black cumin seeds and beyond,” Cancer Therapy, vol. 6, no. b, pp. 495–510, 2008. View at Google Scholar
  13. C. C. Woo, A. P. Kumar, G. Sethi, and K. H. B. Tan, “Thymoquinone: potential cure for inflammatory disorders and cancer,” Biochemical Pharmacology, vol. 83, no. 4, pp. 443–451, 2012. View at Publisher · View at Google Scholar · View at Scopus
  14. M. N. Nagi and M. A. Mansour, “Protective effect of thymoquinone against doxorubicin-induced cardiotoxicity in rats: a possible mechanism of protection,” Pharmacological Research, vol. 41, no. 3, pp. 283–289, 2000. View at Publisher · View at Google Scholar · View at Scopus
  15. O. A. Al-Shabanah, O. A. Badary, M. N. Nagi, N. M. Al-Gharably, A. C. Al-Rikabi, and A. M. Al-Bekairi, “Thymoquinone protects against doxorubicin-induced cardiotoxicity without compromising its antitumor activity,” Journal of Experimental and Clinical Cancer Research, vol. 17, no. 2, pp. 193–198, 1998. View at Google Scholar · View at Scopus
  16. A. E. Edris, “Anti-cancer properties of Nigella spp. essential oils and their major constituents, thymoquinone and β-elemene,” Current Clinical Pharmacology, vol. 4, no. 1, pp. 43–46, 2009. View at Publisher · View at Google Scholar · View at Scopus
  17. R. Keyhanmanesh, M. H. Boskabady, S. Khamneh, and Y. Doostar, “Effect of thymoquinone on the lung pathology and cytokine levels of ovalbumin-sensitized guinea pigs,” Pharmacological Reports, vol. 62, no. 5, pp. 910–916, 2010. View at Publisher · View at Google Scholar · View at Scopus
  18. J. Ravindran, H. B. Nair, B. Sung, S. Prasad, R. R. Tekmal, and B. B. Aggarwal, “Thymoquinone poly (lactide-co-glycolide) nanoparticles exhibit enhanced anti-proliferative, anti-inflammatory, and chemosensitization potential,” Biochemical Pharmacology, vol. 79, no. 11, pp. 1640–1647, 2010. View at Publisher · View at Google Scholar · View at Scopus
  19. S. Kiyonaka, K. Sada, I. Yoshimura, S. Shinkai, N. Kato, and I. Hamachi, “Semi-wet peptide/protein array using supramolecular hydrogel,” Nature Materials, vol. 3, no. 1, pp. 58–64, 2004. View at Publisher · View at Google Scholar · View at Scopus
  20. S. J. Lee and S. Y. Lee, “Microarrays of peptides elevated on the protein layer for efficient protein kinase assay,” Analytical Biochemistry, vol. 330, no. 2, pp. 311–316, 2004. View at Publisher · View at Google Scholar · View at Scopus
  21. G. J. Wegner, H. J. Lee, and R. M. Corn, “Characterization and optimization of peptide arrays for the study of epitope-antibody interactions using surface plasmon resonance imaging,” Analytical Chemistry, vol. 74, no. 20, pp. 5161–5168, 2002. View at Publisher · View at Google Scholar · View at Scopus
  22. A. B. Raschi, E. Romano, A. M. Benavente, A. B. Altabef, and M. E. Tuttolomondo, “Structural and vibrational analysis of thymoquinone,” Spectrochimica Acta—Part A: Molecular and Biomolecular Spectroscopy, vol. 77, no. 2, pp. 497–505, 2010. View at Publisher · View at Google Scholar · View at Scopus
  23. R. C. Young, G. J. Durant, J. C. Emmett et al., “Dipole moment in relation to H2 receptor histamine antagonist activity for cimetidine analogues,” The Journal of Medicinal Chemistry, vol. 29, no. 1, pp. 44–49, 1986. View at Google Scholar · View at Scopus
  24. A. H. Holm, M. Ceccato, R. L. Donkers, L. Fabris, G. Pace, and F. Maran, “Effect of peptide ligand dipole moments on the redox potentials of Au 38 and Au140 nanoparticles,” Langmuir, vol. 22, no. 25, pp. 10584–10589, 2006. View at Publisher · View at Google Scholar · View at Scopus
  25. L. Garbuio, S. Antonello, I. Guryanov et al., “Effect of orientation of the peptide-bridge dipole moment on the properties of fullerene-peptide-radical systems,” Journal of the American Chemical Society, vol. 134, no. 25, pp. 10628–10637, 2012. View at Publisher · View at Google Scholar · View at Scopus
  26. M. J. Frisch, G. W. Trucks, H. B. Schlegel et al., Gaussian 03, Revision C. 02, Gaussian, Wallingford, Conn, USA, 2004.
  27. M. J. Frisch, G. W. Trucks, H. B. Schlegel et al., Gaussian 09 Revision A.1, Gaussian, Wallingford, Conn, USA, 2009.
  28. A. Frisch, A. B. Nielsen, and A. J. Holder, GAUSSIANVIEW Users Manual, Gaussian, Pittsburgh, Pa, USA, 2000.
  29. R. Ditchfield, W. J. Hehre, and J. A. Pople, “Self-consistent molecular orbital methods. 9. Extended Gaussian-type basis for molecular-orbital studies of organic molecules,” The Journal of Chemical Physics, vol. 54, no. 2, pp. 724–728, 1971. View at Google Scholar
  30. A. Ahmadi, N. L. Hadipour, M. Kamfiroozi, and Z. Bagheri, “Theoretical study of aluminum nitride nanotubes for chemical sensing of formaldehyde,” Sensors and Actuators B: Chemical, vol. 161, no. 1, pp. 1025–1029, 2012. View at Publisher · View at Google Scholar · View at Scopus
  31. A. Ahmadi, J. Beheshtian, and N. L. Hadipour, “Chemisorption of NH3 at the open ends of boron nitride nanotubes: a DFT study,” Structural Chemistry, vol. 22, no. 1, pp. 183–188, 2011. View at Publisher · View at Google Scholar · View at Scopus
  32. P. J. Houghton, R. Zarka, B. de las Heras, and J. R. S. Hoult, “Fixed oil of Nigella sativa and derived thymoquinone inhibit eicosanoid generation in leukocytes and membrane lipid peroxidation,” Planta Medica, vol. 61, no. 1, pp. 33–36, 1995. View at Publisher · View at Google Scholar · View at Scopus
  33. N. Chakravarty, “Inhibition of histamine release from mast cells by nigellone,” Annals of Allergy, vol. 70, no. 3, pp. 237–242, 1993. View at Google Scholar · View at Scopus
  34. O. A. Badary, O. A. Al-Shabanah, M. N. Nagi, A. C. Al-Rikabi, and M. M. A. Elmazar, “Inhibition of benzo(a)pyrene-induced forestomach carcinogenesis in mice by thymoquinone,” European Journal of Cancer Prevention, vol. 8, no. 5, pp. 435–440, 1999. View at Publisher · View at Google Scholar · View at Scopus
  35. J. A. Delaire and K. Nakatani, “Linear and nonlinear optical properties of photochromic molecules and materials,” Chemical Reviews, vol. 100, no. 5, pp. 1817–1845, 2000. View at Publisher · View at Google Scholar · View at Scopus
  36. C. Bingel, “Cyclopropanierung von fullerenen,” Chemische Berichte, vol. 126, no. 8, pp. 1957–1959, 1993. View at Publisher · View at Google Scholar
  37. R. S. Ruoff, D. S. Tse, R. Malhotra, and D. C. Lorents, “Solubility of C60 in a variety of solvents,” The Journal of Physical Chemistry, vol. 97, no. 13, pp. 3379–3383, 1993. View at Publisher · View at Google Scholar · View at Scopus