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Journal of Nanomaterials
Volume 2015, Article ID 407437, 7 pages
Research Article

Synthesis and Cytotoxicity of POSS Modified Single Walled Carbon Nanotubes

Institute of Advanced Materials for Nano-Bio Applications, School of Ophthalmology & Optometry, Wenzhou Medical University, 270 Xueyuan Xi Road, Wenzhou, Zhejiang 325027, China

Received 4 December 2014; Revised 24 January 2015; Accepted 3 February 2015

Academic Editor: Andrew R. Barron

Copyright © 2015 Yuhua Xue and Hao Chen. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Single walled carbon nanotubes (SWNTs) decorated with polyhedral oligomeric silsesquioxane (POSS) were synthesized via the amide linkages between the acid treated SWNTs and amine-functionalized POSS. The successful modification of SWNTs with POSS was confirmed by Fourier transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS), and UV-Vis spectra. The resulting SWNTs-POSS can be dispersed in both water and organic solutions. The biocompatibility and cytotoxicity of the SWNTs and SWNTs-POSS were evaluated by CCK-8 viability assays, which indicated that SWNTs-POSS exhibit very extremely low toxicity. The low toxicity of the POSS modified SWNTs leads to more opportunities for using carbon nanotubes in biomedical fields.