Ultra-Sensitive Colorimetric Plasmonic Sensing and Microfluidics for Biofluid Diagnostics Using Nanohole Array

Figure 16

(a) Schematic showing nanohole plasmonic sensor functionalized (immobilized with capturing antibody targeting vesicular stomatitis virus (VSV)) and control sensors (unfunctionalized). (b) Schematic showing VSV attaches only to the antibody immobilized sensor. (c) Transmission spectrum of control sensor without the capture antibody. (d) Transmission spectrum of sensor with the capture antibody showing about 100 nm shift in the resonance peak after the capture of VSV. Adapted from [79] (e) SEM image of the sensor without the virus. (f) Optical image showing the transmitted color by the sensor without the virus. (g) SEM image of the sensor with the virus. (h) Optical image showing the transmitted color is vanished with the capture of virus. Adapted from [70].

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