Table of Contents Author Guidelines Submit a Manuscript
Journal of Nanomaterials
Volume 2015, Article ID 541763, 13 pages
http://dx.doi.org/10.1155/2015/541763
Research Article

Preparation and In Vitro Evaluation of a Multifunctional Iron Silicate@Liposome Nanohybrid for pH-Sensitive Doxorubicin Delivery and Photoacoustic Imaging

1School of Pharmaceutical Sciences, Xiamen University, Xiamen 361102, China
2College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China

Received 30 November 2014; Revised 5 February 2015; Accepted 9 February 2015

Academic Editor: Zehra Durmus

Copyright © 2015 Zehua Liu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. Minow, R. Benjamin, and J. A. Gottlieb, “Cardiomyopath—an overview with determination of risk factors,” Cancer Chemotherapy Reports, vol. 6, p. 195, 1975. View at Google Scholar
  2. J.-M. Escoffre, C. Mannaris, B. Geers et al., “Doxorubicin liposome-loaded microbubbles for contrast imaging and ultrasound-triggered drug delivery,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 60, no. 1, pp. 78–87, 2013. View at Publisher · View at Google Scholar · View at Scopus
  3. Y. Qin, H. Chen, Q. Zhang et al., “Liposome formulated with TAT-modified cholesterol for improving brain delivery and therapeutic efficacy on brain glioma in animals,” International Journal of Pharmaceutics, vol. 420, no. 2, pp. 304–312, 2011. View at Publisher · View at Google Scholar · View at Scopus
  4. Y. Kamimura, K. Furukawa, D. Kittaka, M. Nishio, K. Hamamura, and S. Fukumoto, “Differential enhancing effects of alpha2,8-sialyltransferase on the cell proliferation and mobility,” International Journal of Oncology, vol. 26, no. 2, pp. 337–344, 2005. View at Google Scholar · View at Scopus
  5. M. A. Hussein, L. Wood, E. Hsi et al., “A phase II trial of pegylated liposomal doxorubicin, vincristine, and reduced-dose dexamethasone combination therapy in newly diagnosed multiple myeloma patients,” Cancer, vol. 95, no. 10, pp. 2160–2168, 2002. View at Publisher · View at Google Scholar · View at Scopus
  6. J.-Z. Du, X.-J. Du, C.-Q. Mao, and J. Wang, “Tailor-made dual pH-sensitive polymer-doxorubicin nanoparticles for efficient anticancer drug delivery,” Journal of the American Chemical Society, vol. 133, no. 44, pp. 17560–17563, 2011. View at Publisher · View at Google Scholar · View at Scopus
  7. Z. Teng, X. Zhu, G. Zheng et al., “Ligand exchange triggered controlled-release targeted drug delivery system based on core-shell superparamagnetic mesoporous microspheres capped with nanoparticles,” Journal of Materials Chemistry, vol. 22, no. 34, pp. 17677–17684, 2012. View at Publisher · View at Google Scholar · View at Scopus
  8. J. W. Wojtkowiak, D. Verduzco, K. J. Schramm, and R. J. Gillies, “Drug resistance and cellular adaptation to tumor acidic pH microenvironment,” Molecular Pharmaceutics, vol. 8, no. 6, pp. 2032–2038, 2011. View at Publisher · View at Google Scholar · View at Scopus
  9. B. P. Mahoney, N. Raghunand, B. Baggett, and R. J. Gillies, “Tumor acidity, ion trapping and chemotherapeutics: I. Acid pH affects the distribution of chemotherapeutic agents in vitro,” Biochemical Pharmacology, vol. 66, no. 7, pp. 1207–1218, 2003. View at Publisher · View at Google Scholar · View at Scopus
  10. L. Jing, X. Liang, Z. Deng et al., “Prussian blue coated gold nanoparticles for simultaneous photoacoustic/CT bimodal imaging and photothermal ablation of cancer,” Biomaterials, vol. 35, no. 22, pp. 5814–5821, 2014. View at Publisher · View at Google Scholar · View at Scopus
  11. J. V. Jokerst, D. van de Sompel, S. E. Bohndiek, and S. S. Gambhir, “Cellulose nanoparticles are a biodegradable photoacoustic contrast agent for use in living mice,” Photoacoustics, vol. 2, no. 3, pp. 119–127, 2014. View at Publisher · View at Google Scholar
  12. H. J. Lee, Y. Liu, J. Zhao et al., “In vitro and in vivo mapping of drug release after laser ablation thermal therapy with doxorubicin-loaded hollow gold nanoshells using fluorescence and photoacoustic imaging,” Journal of Controlled Release, vol. 172, no. 1, pp. 152–158, 2013. View at Publisher · View at Google Scholar · View at Scopus
  13. J. M. Tam, J. O. Tam, A. Murthy et al., “Controlled assembly of biodegradable plasmonic nanoclusters for near-infrared imaging and therapeutic applications,” ACS Nano, vol. 4, no. 4, pp. 2178–2184, 2010. View at Publisher · View at Google Scholar · View at Scopus
  14. J. F. Lovell, C. S. Jin, E. Huynh et al., “Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents,” Nature Materials, vol. 10, no. 4, pp. 324–332, 2011. View at Publisher · View at Google Scholar · View at Scopus
  15. W. Fang, J. Yang, J. Gong, and N. Zheng, “Photo- and pH-triggered release of anticancer drugs from mesoporous silica-coated Pd@Ag nanoparticles,” Advanced Functional Materials, vol. 22, no. 4, pp. 842–848, 2012. View at Publisher · View at Google Scholar · View at Scopus
  16. C. Barbé, J. Bartlett, L. Kong et al., “Silica particles: a novel drug-delivery system,” Advanced Materials, vol. 16, no. 21, pp. 1959–1966, 2004. View at Publisher · View at Google Scholar · View at Scopus
  17. D. R. Radu, C.-Y. Lai, K. Jeftinija, E. W. Rowe, S. Jeftinija, and V. S.-Y. Lin, “A polyamidoamine dendrimer-capped mesoporous silica nanosphere-based gene transfection reagent,” Journal of the American Chemical Society, vol. 126, no. 41, pp. 13216–13217, 2004. View at Publisher · View at Google Scholar · View at Scopus
  18. Z. Luo, Y. Hu, K. Cai et al., “Intracellular redox-activated anticancer drug delivery by functionalized hollow mesoporous silica nanoreservoirs with tumor specificity,” Biomaterials, vol. 35, no. 27, pp. 7951–7962, 2014. View at Publisher · View at Google Scholar
  19. S. Santra, P. Zhang, K. Wang, R. Tapec, and W. Tan, “Conjugation of biomolecules with luminophore-doped silica nanoparticles for photostable biomarkers,” Analytical Chemistry, vol. 73, no. 20, pp. 4988–4993, 2001. View at Publisher · View at Google Scholar · View at Scopus
  20. A. Kheirolomoom, L. M. Mahakian, C.-Y. Lai et al., “Copper-doxorubicin as a nanoparticle cargo retains efficacy with minimal toxicity,” Molecular Pharmaceutics, vol. 7, no. 6, pp. 1948–1958, 2010. View at Publisher · View at Google Scholar · View at Scopus
  21. S. Majumder, P. Dutta, A. Mookerjee, and S. K. Choudhuri, “The role of a novel copper complex in overcoming doxorubicin resistance in Ehrlich ascites carcinoma cells in vivo,” Chemico-Biological Interactions, vol. 159, no. 2, pp. 90–103, 2006. View at Publisher · View at Google Scholar · View at Scopus
  22. X. Xu, H. L. Persson, and D. R. Richardson, “Molecular pharmacology of the interaction of anthracyclines with iron,” Molecular Pharmacology, vol. 68, no. 2, pp. 261–271, 2005. View at Publisher · View at Google Scholar · View at Scopus
  23. H. Farhood, N. Serbina, and L. Huang, “The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer,” Biochimica et Biophysica Acta, vol. 1235, no. 2, pp. 289–295, 1995. View at Publisher · View at Google Scholar · View at Scopus
  24. J. Shin, P. Shum, and D. H. Thompson, “Acid-triggered release via dePEGylation of DOPE liposomes containing acid-labile vinyl ether PEG-lipids,” Journal of Controlled Release, vol. 91, no. 1-2, pp. 187–200, 2003. View at Publisher · View at Google Scholar · View at Scopus
  25. P. Liu, M. Chen, C. Chen, X. Fang, X. Chen, and N. Zheng, “An iron silicate based pH-sensitive drug delivery system utilizing coordination bonding,” Journal of Materials Chemistry B, vol. 1, no. 22, pp. 2837–2842, 2013. View at Publisher · View at Google Scholar · View at Scopus
  26. M. Rozenberg, A. Loewenschuss, and Y. Marcus, “IR spectra and hydration of short-chain polyethyleneglycols,” Spectrochimica Acta—Part A: Molecular and Biomolecular Spectroscopy, vol. 54, no. 12, pp. 1819–1826, 1998. View at Publisher · View at Google Scholar · View at Scopus
  27. M. Mrlík, M. Ilčíková, V. Pavlínek, J. Mosnáček, P. Peer, and P. Filip, “Improved thermooxidation and sedimentation stability of covalently-coated carbonyl iron particles with cholesteryl groups and their influence on magnetorheology,” Journal of Colloid and Interface Science, vol. 396, pp. 146–151, 2013. View at Publisher · View at Google Scholar · View at Scopus
  28. Y. Qian, P. Wei, P. Jiang, Z. Li, Y. Yan, and J. Liu, “Preparation of a novel PEG composite with halogen-free flame retardant supporting matrix for thermal energy storage application,” Applied Energy, vol. 106, pp. 321–327, 2013. View at Publisher · View at Google Scholar · View at Scopus
  29. J. Hrkach, D. von Hoff, M. M. Ali et al., “Preclinical development and clinical translation of a PSMA-targeted docetaxel nanoparticle with a differentiated pharmacological profile,” Science Translational Medicine, vol. 4, no. 128, Article ID 128ra39, 2012. View at Publisher · View at Google Scholar · View at Scopus
  30. T. S. Levchenko, R. Rammohan, A. N. Lukyanov, K. R. Whiteman, and V. P. Torchilin, “Liposome clearance in mice: the effect of a separate and combined presence of surface charge and polymer coating,” International Journal of Pharmaceutics, vol. 240, no. 1-2, pp. 95–102, 2002. View at Publisher · View at Google Scholar · View at Scopus
  31. K. Xiao, Y. Li, J. Luo et al., “The effect of surface charge on in vivo biodistribution of PEG-oligocholic acid based micellar nanoparticles,” Biomaterials, vol. 32, no. 13, pp. 3435–3446, 2011. View at Publisher · View at Google Scholar · View at Scopus
  32. A. Akinc, M. Thomas, A. M. Klibanov, and R. Langer, “Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis,” The Journal of Gene Medicine, vol. 7, no. 5, pp. 657–663, 2005. View at Publisher · View at Google Scholar · View at Scopus
  33. U. Lächelt, P. Kos, F. M. Mickler et al., “Fine-tuning of proton sponges by precise diaminoethanes and histidines in pDNA polyplexes,” Nanomedicine: Nanotechnology, Biology, and Medicine, vol. 10, no. 1, pp. 35–44, 2014. View at Publisher · View at Google Scholar · View at Scopus
  34. D. W. Pack, A. S. Hoffman, S. Pun, and P. S. Stayton, “Design and development of polymers for gene delivery,” Nature Reviews Drug Discovery, vol. 4, no. 7, pp. 581–593, 2005. View at Publisher · View at Google Scholar · View at Scopus
  35. P. K. Jain, K. S. Lee, I. H. El-Sayed, and M. A. El-Sayed, “Calculated absorption and scattering properties of gold nanoparticles of different size, shape, and composition: applications in biological imaging and biomedicine,” Journal of Physical Chemistry B, vol. 110, no. 14, pp. 7238–7248, 2006. View at Publisher · View at Google Scholar · View at Scopus
  36. G. P. Luke, D. Yeager, and S. Y. Emelianov, “Biomedical applications of photoacoustic imaging with exogenous contrast agents,” Annals of Biomedical Engineering, vol. 40, no. 2, pp. 422–437, 2012. View at Publisher · View at Google Scholar · View at Scopus
  37. L. An, H. Hu, J. Du et al., “Paramagnetic hollow silica nanospheres for in vivo targeted ultrasound and magnetic resonance imaging,” Biomaterials, vol. 35, no. 20, pp. 5381–5392, 2014. View at Publisher · View at Google Scholar · View at Scopus
  38. E. G. Schutt, D. H. Klein, R. M. Mattrey, and J. G. Riess, “Injectable microbubbles as contrast agents for diagnostic ultrasound imaging: the key role of perfluorochemicals,” Angewandte Chemie—International Edition, vol. 42, no. 28, pp. 3218–3235, 2003. View at Publisher · View at Google Scholar · View at Scopus
  39. W. Luo, W. Ye, and Z. Haiying, “Advances in the researches on endocytosis and cellular localization of nanomaterials and associated mechanisms,” Chinese Journal of Cell Biology, vol. 35, pp. 1826–1831, 2013. View at Google Scholar
  40. J. L. Santos, H. Oliveira, D. Pandita et al., “Functionalization of poly(amidoamine) dendrimers with hydrophobic chains for improved gene delivery in mesenchymal stem cells,” Journal of Controlled Release, vol. 144, no. 1, pp. 55–64, 2010. View at Publisher · View at Google Scholar · View at Scopus
  41. M. Shi, K. Ho, A. Keating, and M. S. Shoichet, “Doxorubicin-conjugated immuno-nanoparticles for intracellular anticancer drug delivery,” Advanced Functional Materials, vol. 19, no. 11, pp. 1689–1696, 2009. View at Publisher · View at Google Scholar · View at Scopus
  42. J. A. MacKay, M. Chen, J. R. McDaniel, W. Liu, A. J. Simnick, and A. Chilkoti, “Self-assembling chimeric polypeptide—doxorubicin conjugate nanoparticles that abolish tumours after a single injection,” Nature Materials, vol. 8, no. 12, pp. 993–999, 2009. View at Publisher · View at Google Scholar · View at Scopus
  43. O. Tacar, P. Sriamornsak, and C. R. Dass, “Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems,” Journal of Pharmacy and Pharmacology, vol. 65, no. 2, pp. 157–170, 2013. View at Publisher · View at Google Scholar · View at Scopus
  44. Q. Zhang, W. Yang, N. Man et al., “Autophagy-mediated chemosensitization in cancer cells by fullerene C60 nanocrystal,” Autophagy, vol. 5, no. 8, pp. 1107–1117, 2009. View at Publisher · View at Google Scholar · View at Scopus