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Journal of Nanomaterials
Volume 2015, Article ID 696918, 12 pages
Review Article

Current Development of Silver Nanoparticle Preparation, Investigation, and Application in the Field of Medicine

1Dental and Craniofacial Research Institute and Division of Growth and Development, Section of Orthodontics, School of Dentistry, University of California, Los Angeles, CA 90095-1759, USA
2California NanoSystems Institute, University of California, Los Angeles, CA 90095, USA
3UCLA Department of Surgery and Department of Orthopaedic Surgery and the Orthopaedic Hospital Research Center, University of California, Los Angeles, CA 90095-1759, USA

Received 15 September 2014; Accepted 14 October 2014

Academic Editor: Xiaoming Li

Copyright © 2015 Maxwell Murphy et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The invited review covers different research areas of silver nanoparticles (AgNPs), including the synthesis strategies of AgNPs, antimicrobial and anti-inflammatory properties of AgNPs, osteoconductive and osteoinductive activities of AgNP-based materials, and potential toxicity of AgNPs. The potential mechanisms of AgNP’s biological efficacy as well as its potential toxicity are discussed as well. In addition, the current development of AgNP applications, especially in the area of therapeutics, is also summarized.